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27-Hydroxycholesterol

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8400432

27-Hydroxycholesterol is a hydroxylation product of cholesterol which is produced by the activity of the enzyme sterol 27-hydroxylase. It activates LXRalpha and LXRbeta in vitro with EC50 values of 85 and 71nM, respectively, and is a potent suppressor of… More details

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Sample Manual Insert View PDF
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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Product Name
27-Hydroxycholesterol, Biochemical
Full Product Name
27-Hydroxycholesterol
Product Synonym Names
(3S, 8S, 9S, 10R, 13R, 14S, 17R)-17-[(2R, 6R)-7-hydroxy-6-methylheptan-2-yl]-10, 13-dimethyl-2, 3, 4, 7, 8, 9, 11, 12, 14, 15, 16, 17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol; (25R)-26-hydroxy Cholesterol; (3beta, 25R)-Cholest-5-ene-3, 26-diol; 25(R)-27-hydroxy Cholesterol
Form/Format
White Solid
Purity/Purification
0.98
Specificity
A hydroxylation product of cholesterol and LXRalpha and LXRbeta activator
Preparation and Storage
Store at -20 degree C
Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Shelf Life: Est.~36 months
Country of Origin: USA
Molecular Weight
402.65
Solubilities
~20mg/ml in Ethanol; ~2mg/ml in DMF; ~0.1mg/ml in DMSO
Molecular Formula
C??H??O?
InChi
InChI=1S/C27H46O2/c1-18(17-28)6-5-7-19(2)23-10-11-24-22-9-8-20-16-21(29)12-14-26(20; 3)25(22)13-15-27(23; 24)4/h8; 18-19; 21-25; 28-29H; 5-7; 9-17H2; 1-4H3/t18-; 19-; 21+; 22+; 23-; 24+; 25+; 26+; 27-/m1/s1
InChi Key
FYHRJWMENCALJY-YSQMORBQSA-N
SMILES
CC(CCCC(C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)O)C)C)CO
CAS Number
20380-11-4
MDL Number
MFCD00272990
PubChem CID
123976

Product References and Citations for 27-Hydroxycholesterol biochemical

https://pubchem.ncbi.nlm.nih.gov/compound/123976

Other Notes

Small volumes of 27-Hydroxycholesterol biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for 27-Hydroxycholesterol purchase

MBS8400432 is a biochemical targeting 27-Hydroxycholesterol.

Additional Details

NCBI/Uniprot data below describe general gene information for 27-Hydroxycholesterol. It may not necessarily be applicable to this product.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
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