Branebrutinib (BMS-986195)

Name: Branebrutinib (BMS-986195); MyBioSource
Brand: MyBioSource
SKU: MBS8400441
Price: 225 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8400441

Branebrutinib is a potent covalent, irreversible inhibitor of Bruton's tyrosine kinase (BTK). BTK is a non-receptor tyrosine kinase. It is a member of the Tec family of kinases and is essential for B cell receptor (BCR) mediated signaling. Branebrutinib… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

Branebrutinib, Biochemical

Full Product Name

Branebrutinib

Product Synonym Names

BMS-986195; 4-[(3S)-3-(but-2-ynoylamino)piperidin-1-yl]-5-fluoro-2, 3-dimethyl-1H-indole-7-carboxamide

Form/Format

White to off-White Solid Powder

Purity/Purification

>98%

Specificity

A potent inhibitor of BTK

Preparation and Storage

Store at -20 degree C
Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Shelf Life: Est.~36 months
Country of Origin: USA

Molecular Weight

370.42

Solubilities

~35mg/ml in DMSO

Molecular Formula

C??H??FN?O?

InChi

InChI=1S/C20H23FN4O2/c1-4-6-16(26)24-13-7-5-8-25(10-13)19-15(21)9-14(20(22)27)18-17(19)11(2)12(3)23-18/h9; 13; 23H; 5; 7-8; 10H2; 1-3H3; (H2; 22; 27)(H; 24; 26)/t13-/m0/s1

InChi Key

VJPPLCNBDLZIFG-ZDUSSCGKSA-N

SMILES

CC#CC(=O)NC1CCCN(C1)C2=C(C=C(C3=C2C(=C(N3)C)C)C(=O)N)F

CAS Number

1912445-55-6

MDL Number

MFCD31631584

PubChem CID

121293929

Product Categories/Family for Branebrutinib biochemical

Web Categories; Enzyme Inhibitors; Protein Kinase Inhibitors; Protein Kinase Inhibitors (A-Z); Protein Kinase Inhibitors; Bruton's Tyrosine Kinase (BTK) Inhibitors; Enzyme Inhibitors (A-Z); Biochemicals; Biochemicals (A-Z); Signal Transduction; Protein Ki

Product References and Citations for Branebrutinib biochemical

https://pubchem.ncbi.nlm.nih.gov/compound/121293929

Other Notes

Small volumes of Branebrutinib biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Branebrutinib purchase

MBS8400441 is a biochemical targeting Branebrutinib.