Allitinib (AST-1306)

Name: Allitinib (AST-1306); MyBioSource
Brand: MyBioSource
SKU: MBS8400443
Price: 245 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8400443

Allitinib is a novel anilino-quinazoline compound that inhibits ErbB tyrosine kinases: epidermal growth factor receptor (EGFR) and ErbB2. It inhibits EGFR and ErbB2 with IC50 values of 0.5nM and 3nM in cell-free assays. It inhibits the phosphorylation of EGFR… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

Allitinib, Biochemical

Full Product Name

Allitinib

Product Synonym Names

AST-1306; N-(4-(3-Chloro-4-(3-fluorobenzyloxy)phenylamino)quinazolin-6-yl)acrylamide; N-[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]quinazolin-6-yl]prop-2-enamide

Form/Format

Solid

Purity/Purification

>98%

Specificity

An irreversible ErbB2 and EGFR inhibitor

Preparation and Storage

Store at -20 degree C
Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Shelf Life: Est.~36 months
Country of Origin: USA

Molecular Weight

448.9

Solubilities

~20mg/ml in DMSO

Molecular Formula

C??H??ClFN?O?

InChi

InChI=1S/C24H18ClFN4O2/c1-2-23(31)29-17-6-8-21-19(11-17)24(28-14-27-21)30-18-7-9-22(20(25)12-18)32-13-15-4-3-5-16(26)10-15/h2-12; 14H; 1; 13H2; (H; 29; 31)(H; 27; 28; 30)

InChi Key

MVZGYPSXNDCANY-UHFFFAOYSA-N

SMILES

C=CC(=O)NC1=CC2=C(C=C1)N=CN=C2NC3=CC(=C(C=C3)OCC4=CC(=CC=C4)F)Cl

CAS Number

897383-62-9

MDL Number

MFCD17169993

PubChem CID

24739943

Product Categories/Family for Allitinib biochemical

Web Categories; Enzyme Inhibitors; Protein Kinase Inhibitors; Protein Kinase Inhibitors (A-Z); Enzyme Inhibitors (A-Z); Biochemicals; Biochemicals (A-Z); Other Protein Kinase Inhibitors

Product References and Citations for Allitinib biochemical

https://pubchem.ncbi.nlm.nih.gov/compound/24739943

Other Notes

Small volumes of Allitinib biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Allitinib purchase

MBS8400443 is a biochemical targeting Allitinib.