Icotinib (BPI-2009)

Name: Icotinib (BPI-2009); MyBioSource
Brand: MyBioSource
SKU: MBS8400444
Price: 245 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8400444

Icotininb is a potent epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) with an IC50 of 5nM. It blocks EGFR-mediated intracellular tyrosine phosphorylation IC50 of 45nM in the human epidermoid carcinoma A431 cell line and inhibits tumor… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

Icotinib, Biochemical

Full Product Name

Icotinib

Product Synonym Names

BPI-2009; BPI-2009H; N-(3-ethynylphenyl)-7, 8, 10, 11, 13, 14-hexahydro-[1, 4, 7, 10]tetraoxacyclododecino[2, 3-g]quinazolin-4-amine; Conmana; (3-Ethynyl-phenyl)(7, 8, 10, 11, 13, 14-hexahydro-6, 9, 12, 15-tetraoxa-1, 3-diazacyclododeca[b]naphthalen-4-yl)-amine; N-(3-ethynylphenyl)-2, 5, 8, 11-tetraoxa-15, 17-diazatricyclo[10.8.0.014, 19]icosa-1(12), 13, 15, 17, 19-pentaen-18-amine

Form/Format

Solid

Purity/Purification

>99%

Specificity

A potent EGFR inhibitor

Preparation and Storage

Store at -20 degree C
Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Shelf Life: Est.~36 months
Country of Origin: USA

Molecular Weight

391.4

Solubilities

~75mg/ml in DMSO

Molecular Formula

C??H??N?O?

InChi

InChI=1S/C22H21N3O4/c1-2-16-4-3-5-17(12-16)25-22-18-13-20-21(14-19(18)23-15-24-22)29-11-9-27-7-6-26-8-10-28-20/h1; 3-5; 12-15H; 6-11H2; (H; 23; 24; 25)

InChi Key

QQLKULDARVNMAL-UHFFFAOYSA-N

SMILES

C#CC1=CC(=CC=C1)NC2=NC=NC3=CC4=C(C=C32)OCCOCCOCCO4

CAS Number

610798-31-7

MDL Number

MFCD22124501

PubChem CID

22024915

Product Categories/Family for Icotinib biochemical

Web Categories; Enzyme Inhibitors; Protein Kinase Inhibitors; Protein Kinase Inhibitors (A-Z); Biochemicals; Biochemicals (A-Z); Signal Transduction; Protein Kinases; Protein Tyrosine Kinase Inhibitors; Anticancer Agents; Nibs; Enzyme Inhibitors (A-Z); Ca

Product References and Citations for Icotinib biochemical

https://pubchem.ncbi.nlm.nih.gov/compound/22024915

Other Notes

Small volumes of Icotinib biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Icotinib purchase

MBS8400444 is a biochemical targeting Icotinib.