Capmatinib (INC280)

Name: Capmatinib (INC280); MyBioSource
Brand: MyBioSource
SKU: MBS8400446
Price: 205 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8400446

Capmatinib is an ATP competitive inhibitor of c-MET kinase or hepatocyte growth factor receptor (HGFR). Binding of Hepatocyt Growth Factor to c-MET receptor causes activation of multiple downstream pathways. Capmatinib potently inhibits in vitro kinase… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

Capmatinib, Biochemical

Full Product Name

Capmatinib

Product Synonym Names

INC280; INCB28060; INC28060; 2-fluoro-N-methyl-4-(7-(quinolin-6-ylmethyl)imidazo[1, 2-b][1, 2, 4]triazin-2-yl)benzamide

Form/Format

Yellow solid powder

Purity/Purification

>98%

Specificity

An ATP competitive inhibitor of c-MET kinase

Preparation and Storage

Store at -20 degree C
Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Shelf Life: Est.~36 months
Country of Origin: USA

Molecular Weight

412.4

Solubilities

~0.3mg/ml in DMSO; ~1mg/ml in DMF

Molecular Formula

C??H??FN?O

InChi

InChI=1S/C23H17FN6O/c1-25-22(31)18-6-5-16(11-19(18)24)21-13-28-23-27-12-17(30(23)29-21)10-14-4-7-20-15(9-14)3-2-8-26-20/h2-9; 11-13H; 10H2; 1H3; (H; 25; 31)

InChi Key

LIOLIMKSCNQPLV-UHFFFAOYSA-N

SMILES

CNC(=O)C1=C(C=C(C=C1)C2=NN3C(=CN=C3N=C2)CC4=CC5=C(C=C4)N=CC=C5)F

CAS Number

1029712-80-8

MDL Number

MFCD18633285

PubChem CID

25145656

Product Categories/Family for Capmatinib biochemical

Web Categories; Enzyme Inhibitors; Protein Kinase Inhibitors; Protein Kinase Inhibitors (A-Z); Enzyme Inhibitors (A-Z); Biochemicals; Biochemicals (A-Z); Other Protein Kinase Inhibitors

Product References and Citations for Capmatinib biochemical

https://pubchem.ncbi.nlm.nih.gov/compound/25145656

Other Notes

Small volumes of Capmatinib biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Capmatinib purchase

MBS8400446 is a biochemical targeting Capmatinib.