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Savolitinib (Volitinib)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8400447

Savolitinib is an inhibitor of cMET tyrosine kinase or hepatocyte growth factor receptor (HGFR). It potently inhibits the tyrosine kinase activity of recombinant cMET in vitro with an IC50 value of 4nM. It inhibits proliferation of cell lines SNU?5, SNU?638,… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
Savolitinib, Biochemical
Full Product Name
Savolitinib
Product Synonym Names
Volitinib; AZD 6094; HM 5016504; HMPL 504; 3-[(1S)-1-imidazo[1, 2-a]pyridin-6-ylethyl]-5-(1-methylpyrazol-4-yl)triazolo[4, 5-b]pyrazine; (S)-1-(1-(imidazo[1, 2-a]pyridin-6-yl)ethyl)-6-(1-methyl-1H-pyrazol-4-yl)-1H-[1, 2, 3]triazolo[4, 5-b]pyrazine; 4-{1-[(1S)-1-{imidazo[1, 2-a]pyridin-6-yl}ethyl]-1H-[1, 2, 3]triazolo[4, 5-b]pyrazin-6-yl}-1-methyl-1H-pyrazole
Form/Format
White to off-white powder
Purity/Purification
>98%
Specificity
An inhibitor of cMET tyrosine kinase
Preparation and Storage
Store at -20 degree C
Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Shelf Life: Est.~36 months
Country of Origin: USA
Molecular Weight
345.4
Solubilities
~16mg/ml in DMSO
Molecular Formula
C??H??N?
InChi
InChI=1S/C17H15N9/c1-11(12-3-4-15-18-5-6-25(15)10-12)26-17-16(22-23-26)19-8-14(21-17)13-7-20-24(2)9-13/h3-11H; 1-2H3/t11-/m0/s1
InChi Key
XYDNMOZJKOGZLS-NSHDSACASA-N
SMILES
CC(C1=CN2C=CN=C2C=C1)N3C4=NC(=CN=C4N=N3)C5=CN(N=C5)C
CAS Number
1313725-88-0
MDL Number
MFCD28359096
PubChem CID
68289010

Product References and Citations for Savolitinib biochemical

https://pubchem.ncbi.nlm.nih.gov/compound/68289010

Other Notes

Small volumes of Savolitinib biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Savolitinib purchase

MBS8400447 is a biochemical targeting Savolitinib.
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