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LM22B-10

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8400459

LM22B-10 is an activator of Tropomyosin-receptor kinase neurotrophin receptors TrkB and TrkC. It binds to TrkB and TrkC in a dose-dependent manner at concentrations of 250nM-2000nM. It increases cell survival and accelerates neurite outgrowth. LM22B-10… More details

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Product Documentation
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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Product Name
LM22B-10, Biochemical
Full Product Name
LM22B-10
Product Gene Name
LM22B-10 biochemical
Product Synonym Names
2-[4-[[4-[bis(2-hydroxyethyl)amino]phenyl]-(4-chlorophenyl)methyl]-N-(2-hydroxyethyl)anilino]ethanol; 4, 4'-(4-Chlorobenzylidene)bis[N, N-bis(2-hydroxyethyl)aniline]; 2, 2', 2'', 2'''-[[(4-chlorophenyl)methylene]bis(4, 1-phenylenenitrilo)]tetrakis-ethanol; 2, 2', 2'', 2'''-((((4-chlorophenyl)methylene)bis(4, 1-phenylene))bis(azanetriyl))tetraethanol
Form/Format
Pale grey solid
Purity/Purification
>98%
Specificity
An activator of Tropomyosin-receptor kinase neurotrophin receptors TrkB and TrkC
Preparation and Storage
Store at -20 degree C
Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Shelf Life: Est.~36 months
Country of Origin: USA
Molecular Weight
485
Solubilities
~30mg/ml in DMSO
Molecular Formula
C??H??ClN?O?
InChi
InChI=1S/C27H33ClN2O4/c28-24-7-1-21(2-8-24)27(22-3-9-25(10-4-22)29(13-17-31)14-18-32)23-5-11-26(12-6-23)30(15-19-33)16-20-34/h1-12; 27; 31-34H; 13-20H2
InChi Key
QCXQLSGBOUUVNH-UHFFFAOYSA-N
SMILES
C1=CC(=CC=C1C(C2=CC=C(C=C2)N(CCO)CCO)C3=CC=C(C=C3)Cl)N(CCO)CCO
CAS Number
342777-54-2
MDL Number
MFCD00005622
PubChem CID
542158

Product Categories/Family for LM22B-10 biochemical

Web Categories; Enzyme Inhibitors; Enzyme Inhibitors (A-Z); Biochemicals; Protein Kinase Inhibitors; Protein Kinase Inhibitors (A-Z); Biochemicals (A-Z); Signal Transduction; Protein Kinases; Protein Tyrosine Kinase Inhibitors; Activators-Inducers; Agonis

Structure of LM22B-10 biochemical

LM22B-10 Biochemical – Cat# MBS8400459

Product References and Citations for LM22B-10 biochemical

https://pubchem.ncbi.nlm.nih.gov/compound/542158

Other Notes

Small volumes of LM22B-10 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for LM22B-10 purchase

MBS8400459 is a biochemical targeting LM22B-10.
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