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Narasin

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8400461

Narasin is an ionophore antibiotic which is a derivative of salinomycin. It modifies the permeability of cellular membranes to cationic metal species. It inhibits NF-kappaB signaling via inhibition of IkappaBalpha phosphorylation with an IC50 of 3.2uM.… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Product Name
Narasin, Biochemical
Full Product Name
Narasin
Product Synonym Names
(4S)-4-Methylsalinomycin; (2R)-2-[(2R, 3S, 5S, 6R)-6-[(2S, 3S, 4S, 6R)-6-[(3S, 5S, 7R, 9S, 10S, 12R, 15R)-3-[(2R, 5R, 6S)-5-ethyl-5-hydroxy-6-methyloxan-2-yl]-15-hydroxy-3, 10, 12-trimethyl-4, 6, 8-trioxadispiro[4.1.57.35]pentadec-13-en-9-yl]-3-hydroxy-4-methyl-5-oxooctan-2-yl]-3, 5-dimethyloxan-2-yl]butanoic acid; narasin A; Monteban; 2H-Pyran-2-acetic acid, alpha-ethyl-6-(5-(2-(5-ethyltetrahydro-5-hydroxy-6-methyl-2H-pyran-2-yl)-15-hydroxy-2, 10, 12-trimethyl-1, 6, 8-trioxadispiro(4.1.5.3)pentadec-13-en-9-yl)-2-hydroxy-1, 3-dimethyl-4-oxoheptyl)tetrahydro-3, 5-dimethyl-; A 28086A; Antibiotic A 28086A
Form/Format
White to off-white Solid
Purity/Purification
>95%
Specificity
An ionophore antibiotic
Preparation and Storage
Store at -20 degree C
Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Shelf Life: Est.~36 months
Country of Origin: USA
Molecular Weight
765.03
Solubilities
Soluble in DMSO
Molecular Formula
C??H??O??
InChi
InChI=1S/C43H72O11/c1-12-30(35(46)27(8)34(45)28(9)36-23(4)21-24(5)37(51-36)31(13-2)39(47)48)38-25(6)22-26(7)42(52-38)18-15-32(44)43(54-42)20-19-40(11; 53-43)33-16-17-41(49; 14-3)29(10)50-33/h15; 18; 23-34; 36-38; 44-45; 49H; 12-14; 16-17; 19-22H2; 1-11H3; (H; 47; 48)/t23-; 24-; 25-; 26+; 27-; 28-; 29-; 30-; 31+; 32+; 33+; 34+; 36+; 37+; 38-; 40-; 41+; 42-; 43-/m0/s1
InChi Key
VHKXXVVRRDYCIK-CWCPJSEDSA-N
SMILES
CCC(C1C(CC(C(O1)C(C)C(C(C)C(=O)C(CC)C2C(CC(C3(O2)C=CC(C4(O3)CCC(O4)(C)C5CCC(C(O5)C)(CC)O)O)C)C)O)C)C)C(=O)O
CAS Number
55134-13-9
MDL Number
MFCD00133653
PubChem CID
65452

Structure of Narasin biochemical

Narasin Biochemical – Cat# MBS8400461

Product References and Citations for Narasin biochemical

https://pubchem.ncbi.nlm.nih.gov/compound/65452

Other Notes

Small volumes of Narasin biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Narasin purchase

MBS8400461 is a biochemical targeting Narasin.
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