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Licogliflozin (LIK066)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8400469

Licogliflozin is a dual inhibitor of Sodium/glucose cotransporters SGLT1 and SGLT2 with a higher selectivity for SGLT2 (in vitro IC50 values of 20.6 and 0.58nM, respectively). It causes a reduction in body weight from baseline versus placebo after 24 weeks… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
Licogliflozin, Biochemical
Full Product Name
Licogliflozin
Product Synonym Names
LIK066; (2S, 3R, 4R, 5S, 6R)-2-[3-(2, 3-dihydro-1, 4-benzodioxin-6-ylmethyl)-4-ethylphenyl]-6-(hydroxymethyl)oxane-3, 4, 5-triol; (2S, 3R, 4R, 5S, 6R)-2-[3-(2, 3-dihydro-benzo[1, 4]dioxin-6-ylmethyl)-4-ethyl-phenyl]-6-hydroxymethyl-tetrahydro-pyran-3, 4, 5-triol
Form/Format
Solid
Purity/Purification
>=98%
Specificity
A dual inhibitor of Sodium/glucose cotransporters SGLT1 and SGLT2
Preparation and Storage
Store at -20 degree C
Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Shelf Life: Est.~36 months
Country of Origin: USA
Molecular Weight
416.46
Solubilities
Soluble in DMSO
Molecular Formula
C??H??O?
InChi
InChI=1S/C23H28O7/c1-2-14-4-5-15(23-22(27)21(26)20(25)19(12-24)30-23)11-16(14)9-13-3-6-17-18(10-13)29-8-7-28-17/h3-6; 10-11; 19-27H; 2; 7-9; 12H2; 1H3/t19-; 20-; 21+; 22-; 23+/m1/s1
InChi Key
XFJAMQQAAMJFGB-ZQGJOIPISA-N
SMILES
CCC1=C(C=C(C=C1)C2C(C(C(C(O2)CO)O)O)O)CC3=CC4=C(C=C3)OCCO4
CAS Number
1291094-73-9
MDL Number
MFCD31630771
PubChem CID
52913524

Product References and Citations for Licogliflozin biochemical

https://pubchem.ncbi.nlm.nih.gov/compound/52913524

Other Notes

Small volumes of Licogliflozin biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Licogliflozin purchase

MBS8400469 is a biochemical targeting Licogliflozin.
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