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Pretomanid (PA-824)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8400474

Pretomanid is a nitroimidazopyran active againt Mycobacterium tuberculosis. It is active against multidrug-resistant M. tuberculosis clinical isolates with MIC More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
Pretomanid, Biochemical
Full Product Name
Pretomanid (PA-824)
Product Synonym Names
(6S)-2-nitro-6-[[4-(trifluoromethoxy)phenyl]methoxy]-6, 7-dihydro-5H-imidazo[2, 1-b][1, 3]oxazine; (S)-2-Nitro-6-((4-(trifluoromethoxy)benzyl)oxy)-6, 7-dihydro-5H-imidazo[2, 1-b][1, 3]oxazine; (3S)-8-nitro-3-[[4-(trifluoromethoxy)phenyl]methoxy]-5-oxa-1, 7-diazabicyclo[4.3.0]nona-6, 8-diene
Form/Format
White to Pale Yellow Solid
Purity/Purification
>=95%
Specificity
A nitroimidazopyran active againt Mycobacterium tuberculosis
Preparation and Storage
Store at -20 degree C
Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Shelf Life: Est.~36 months
Country of Origin: USA
Molecular Weight
359.26
Solubilities
~5mg/ml in DMSO (may need warming orultrasonication)
Molecular Formula
C??H??F?N?O?
InChi
InChI=1S/C14H12F3N3O5/c15-14(16; 17)25-10-3-1-9(2-4-10)7-23-11-5-19-6-12(20(21)22)18-13(19)24-8-11/h1-4; 6; 11H; 5; 7-8H2/t11-/m0/s1
InChi Key
ZLHZLMOSPGACSZ-NSHDSACASA-N
SMILES
C1C(COC2=NC(=CN21)[N+](=O)[O-])OCC3=CC=C(C=C3)OC(F)(F)F
CAS Number
187235-37-6
MDL Number
MFCD06809939
PubChem CID
456199

Product References and Citations for Pretomanid biochemical

https://pubchem.ncbi.nlm.nih.gov/compound/456199

Other Notes

Small volumes of Pretomanid biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Pretomanid purchase

MBS8400474 is a biochemical targeting Pretomanid. Also known as Pretomanid (PA-824).
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