• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

Siponimod (BAF-312)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8400477

Siponimod is an orally bioavailable agonist of the sphingosine-1-phosphate (S1P) receptor that is selective for S1P1 and S1P5 with EC50 values of 0.39 and 0.98nM respectively, in a GTPgammaS-binding assay. Siponimod (0.3 or 3mg/kg/daymg/kg/day) reduces… More details

DISCONTINUED
Click here to view our similar product(s) OR click here to contact our technical support team for suitable replacement.
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Product Name
Siponimod, Biochemical
Full Product Name
Siponimod (BAF-312)
Product Synonym Names
1-[[4-[(E)-N-[[4-cyclohexyl-3-(trifluoromethyl)phenyl]methoxy]-C-methylcarbonimidoyl]-2-ethylphenyl]methyl]azetidine-3-carboxylic acid; 3-Azetidinecarboxylic acid, 1-((4-((1E)-1-(((4-cyclohexyl-3-(trifluoromethyl)phenyl)methoxy)imino)ethyl)-2-ethylphenyl)methyl); 1-{4-[1-((E)-4-cyclohexyl-3-trifluoromethyl-benzyloxyimino)-ethyl]-2-ethyl-benzyl}-azetidine-3-carboxylic acid
Form/Format
White to off-white solid powder
Purity/Purification
>=98%
Specificity
An agonist of the S1P1 and SIP5 receptors
Preparation and Storage
Store at -20 degree C
Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Shelf Life: Est.~36 months
Country of Origin: USA
Molecular Weight
516.6
Solubilities
~16mg/ml in DMF; ~3mg/ml in ethanol; ~20mg/ml in DMSO
Molecular Formula
C??H??F?N?O?
InChi
InChI=1S/C29H35F3N2O3/c1-3-21-14-23(10-11-24(21)15-34-16-25(17-34)28(35)36)19(2)33-37-18-20-9-12-26(22-7-5-4-6-8-22)27(13-20)29(30; 31)32/h9-14; 22; 25H; 3-8; 15-18H2; 1-2H3; (H; 35; 36)/b33-19+
InChi Key
KIHYPELVXPAIDH-HNSNBQBZSA-N
SMILES
CCC1=C(C=CC(=C1)C(=NOCC2=CC(=C(C=C2)C3CCCCC3)C(F)(F)F)C)CN4CC(C4)C(=O)O
CAS Number
1230487-00-9
MDL Number
MFCD26142651
PubChem CID
44599207

Product Categories/Family for Siponimod biochemical

Web Categories; Immunology; Autoimmunity; Biochemicals; Biochemicals (A-Z); Neuroscience; Neuroprotective agents

Structure of Siponimod biochemical

Siponimod (BAF-312) Biochemical – Cat# MBS8400477

Product References and Citations for Siponimod biochemical

https://pubchem.ncbi.nlm.nih.gov/compound/44599207

Other Notes

Small volumes of Siponimod biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Siponimod purchase

MBS8400477 is a biochemical targeting Siponimod. Also known as Siponimod (BAF-312).
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000