Astemizole (Hismanal)

Name: Astemizole (Hismanal); MyBioSource
Brand: MyBioSource
SKU: MBS8400490
Price: 185 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8400490

Astemizole is a histamine H1-receptor antagonist, with an IC50 of 4nM. Astemizole also shows potent hERG potassium channel blocking activity with an IC50 of 0.9nM. Astemizole shows synergistic antiproliferative effects with calcitriol in breast cancer cells… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

Astemizole, Biochemical

Full Product Name

Astemizole

Product Synonym Names

Hismanal; Histaminos; Paralergin; NSC 329963; 1-[(4-fluorophenyl)methyl]-N-[1-[2-(4-methoxyphenyl)ethyl]piperidin-4-yl]benzimidazol-2-amine; 1-(p-Fluorobenzyl)-2-((1-(2-(p-methoxyphenyl)ethyl)piperid-4-yl)amino)benzimidazole; R 43512

Form/Format

White solid

Purity/Purification

>=98%

Specificity

A histamine H1-receptor antagonist and hERG potassium channel blocker

Preparation and Storage

Store at -20 degree C
Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Shelf Life: Est.~36 months
Country of Origin: USA

Molecular Weight

458.6

Solubilities

~ 5mg/ml in ethanol; ~10mg/ml in DMF; ~20mg/ml in DMSO

Molecular Formula

C??H??FN?O

InChi

InChI=1S/C28H31FN4O/c1-34-25-12-8-21(9-13-25)14-17-32-18-15-24(16-19-32)30-28-31-26-4-2-3-5-27(26)33(28)20-22-6-10-23(29)11-7-22/h2-13; 24H; 14-20H2; 1H3; (H; 30; 31)

InChi Key

GXDALQBWZGODGZ-UHFFFAOYSA-N

SMILES

COC1=CC=C(C=C1)CCN2CCC(CC2)NC3=NC4=CC=CC=C4N3CC5=CC=C(C=C5)F

CAS Number

68844-77-9

MDL Number

MFCD00153919

PubChem CID

2247

Product Categories/Family for Astemizole biochemical

Web Categories; Biochemicals; Biochemicals (A-Z); Anticancer Agents; Coronavirus

Product References and Citations for Astemizole biochemical

https://pubchem.ncbi.nlm.nih.gov/compound/2247

Other Notes

Small volumes of Astemizole biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Astemizole purchase

MBS8400490 is a biochemical targeting Astemizole.