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RIPA-56

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8400491

RIPA-56 is a highly potent, selective, and metabolically stable inhibitor of Receptor-Interacting Protein 1 (RIP1) kinase with an IC50 of 13nM. It protects HT-29 cells against TNFalpha-induced necroptosis with an EC50 of 28nM. RIPA-56 efficiently reduces… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
RIPA-56, Biochemical
Full Product Name
RIPA-56
Product Synonym Names
N-benzyl-N-hydroxy-2, 2-dimethylbutanamide
Form/Format
White to beige powder
Purity/Purification
>=98%
Specificity
A highly potent and selective inhibitor of Receptor-Interacting Protein 1 (RIP1) kinase
Preparation and Storage
Store at -20 degree C
Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Shelf Life: Est.~36 months
Country of Origin: USA
Molecular Weight
221.29
Solubilities
~2mg/ml in DMSO
Molecular Formula
C??H??NO?
InChi
InChI=1S/C13H19NO2/c1-4-13(2; 3)12(15)14(16)10-11-8-6-5-7-9-11/h5-9; 16H; 4; 10H2; 1-3H3
InChi Key
AVYVHIKSFXVDBG-UHFFFAOYSA-N
SMILES
CCC(C)(C)C(=O)N(CC1=CC=CC=C1)O
CAS Number
1956370-21-0
MDL Number
MFCD30738006
PubChem CID
121439991

Product Categories/Family for RIPA-56 biochemical

Web Categories; Biochemicals; Enzyme Inhibitors; Protein Kinase Inhibitors; Protein Kinase Inhibitors (A-Z); Immunology; Autoimmunity; Biochemicals (A-Z); Enzyme Inhibitors (A-Z); Coronavirus

Structure of RIPA-56 biochemical

RIPA-56 Biochemical – Cat# MBS8400491

Product References and Citations for RIPA-56 biochemical

https://pubchem.ncbi.nlm.nih.gov/compound/121439991

Other Notes

Small volumes of RIPA-56 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for RIPA-56 purchase

MBS8400491 is a biochemical targeting RIPA-56.
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