Siramesine (Lu-28-179)

Name: Siramesine (Lu-28-179); MyBioSource
Brand: MyBioSource
SKU: MBS8400493
Price: 210 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8400493

Siramesine is an agonist for sigma-2 (sigma2) receptor. It is selective for sigma2 over sigma1 with IC50 values of 0.12nM and 17nM respectively. It shows potent anxiolytic-like effects in rodents. The minimal effective dose (MED) is 0.18nMol/kg (0.1… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

Siramesine, Biochemical

Full Product Name

Siramesine

Product Synonym Names

Lu-28-179; 1'-[4-[1-(4-fluorophenyl)indol-3-yl]butyl]spiro[1H-2-benzofuran-3, 4'-piperidine]; 1'-(4-(1-(p-Fluorophenyl)indol-3-yl)butyl)spiro(phthalan-1, 4'-piperidine)

Form/Format

White solid

Purity/Purification

>=98%

Specificity

An agonist for sigma-2 receptor

Preparation and Storage

Store at -20 degree C
Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Shelf Life: Est.~36 months
Country of Origin: USA

Molecular Weight

454.6

Solubilities

~25mg/ml in DMSO

Molecular Formula

C??H??FN?O

InChi

InChI=1S/C30H31FN2O/c31-25-12-14-26(15-13-25)33-21-23(27-9-2-4-11-29(27)33)7-5-6-18-32-19-16-30(17-20-32)28-10-3-1-8-24(28)22-34-30/h1-4; 8-15; 21H; 5-7; 16-20; 22H2

InChi Key

XWAONOGAGZNUSF-UHFFFAOYSA-N

SMILES

C1CN(CCC12C3=CC=CC=C3CO2)CCCCC4=CN(C5=CC=CC=C54)C6=CC=C(C=C6)F

CAS Number

147817-50-3

MDL Number

MFCD00912182

PubChem CID

9829526

Product Categories/Family for Siramesine biochemical

Web Categories; Biochemicals; Biochemicals (A-Z); Activators-Inducers; Agonists; Other Agonists; Neuroscience; Neuroprotective agents; Coronavirus

Product References and Citations for Siramesine biochemical

https://pubchem.ncbi.nlm.nih.gov/compound/9829526

Other Notes

Small volumes of Siramesine biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Siramesine purchase

MBS8400493 is a biochemical targeting Siramesine.