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Tucidinostat (Chidamide)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8400499

Tucidinostat is an inhibitor of histone deacetylases (HDACs) with IC50 values of 95nM, 160nM, 67nM and 78nM for HDAC1, HDAC2, HDAC3 and HDAC10 respectively. It shows potent antitumor activity. It inhibits several human derived tumor cell lines, such as HL-60,… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
Tucidinostat, Biochemical
Full Product Name
Tucidinostat
Product Synonym Names
Chidamide; Epidaza; N-(2-amino-4-fluorophenyl)-4-[[[(E)-3-pyridin-3-ylprop-2-enoyl]amino]methyl]benzamide; (E)-N-(2-amino-4-fluorophenyl)-4-((3-(pyridin-3-yl)acrylamido)methyl)benzamide; N-(2-Amino-4-fluorophenyl)-4-(((1-oxo-3-(3-pyridinyl)-2-propen-1-yl)amino)methyl)benzamide; CS-055; HBI-8000
Form/Format
Off white Solid
Purity/Purification
>=98%
Specificity
An inhibitor of histone deacetylases
Preparation and Storage
Store at -20 degree C
Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Shelf Life: Est.~36 months
Country of Origin: USA
Molecular Weight
390.41
Solubilities
~20mg/ml in DMSO and DMF
Molecular Formula
C??H??FN?O?
InChi
InChI=1S/C22H19FN4O2/c23-18-8-9-20(19(24)12-18)27-22(29)17-6-3-16(4-7-17)14-26-21(28)10-5-15-2-1-11-25-13-15/h1-13H; 14; 24H2; (H; 26; 28)(H; 27; 29)/b10-5+
InChi Key
SZMJVTADHFNAIS-BJMVGYQFSA-N
SMILES
C1=CC(=CN=C1)C=CC(=O)NCC2=CC=C(C=C2)C(=O)NC3=C(C=C(C=C3)F)N
CAS Number
1616493-44-7
MDL Number
MFCD28100259
PubChem CID
12136798

Product References and Citations for Tucidinostat biochemical

https://pubchem.ncbi.nlm.nih.gov/compound/12136798

Other Notes

Small volumes of Tucidinostat biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Tucidinostat purchase

MBS8400499 is a biochemical targeting Tucidinostat.
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