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BAY-677

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8400500

BAY-677 is a negative control for BAY-678. BAY-678 is a potent, selective and cell-permeable inhibitor of human neutrophil elastase (HNE) with an IC50 of 20nM. The S-enantiomer BAY-677 inhibits HNE with IC50>2000nM. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
BAY-677, Biochemical
Full Product Name
BAY-677
Product Gene Name
BAY-677 biochemical
Product Synonym Names
5-[(6S)-5-acetyl-4-methyl-2-oxo-3-[3-(trifluoromethyl)phenyl]-1, 6-dihydropyrimidin-6-yl]pyridine-2-carbonitrile; 5-[(4S)-5-Acetyl-1, 2, 3, 4-tetrahydro-6-methyl-2-oxo-1-[3-(trifluoromethyl)phenyl]-4-pyrimidinyl]-2-pyridinecarbonitrile
Form/Format
Yellow solid
Purity/Purification
>=97%
Specificity
A negative control for BAY-678
Preparation and Storage
Store at -20 degree C
Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Shelf Life: Est.~36 months
Country of Origin: USA
Molecular Weight
400.35
Solubilities
~20mg/ml in DMSO
Molecular Formula
C??H??F?N?O?
InChi
InChI=1S/C20H15F3N4O2/c1-11-17(12(2)28)18(13-6-7-15(9-24)25-10-13)26-19(29)27(11)16-5-3-4-14(8-16)20(21; 22)23/h3-8; 10; 18H; 1-2H3; (H; 26; 29)/t18-/m0/s1
InChi Key
PGIVGIFOWOVINL-SFHVURJKSA-N
SMILES
CC1=C(C(NC(=O)N1C2=CC=CC(=C2)C(F)(F)F)C3=CN=C(C=C3)C#N)C(=O)C
CAS Number
2117404-84-7
MDL Number
MFCD30146413
PubChem CID
68944900

Product Categories/Family for BAY-677 biochemical

Web Categories; Biochemicals; Enzyme Inhibitors; Protease Inhibitors; Enzyme Inhibitors (A-Z); Biochemicals (A-Z); Elastase Inhibitors

Structure of BAY-677 biochemical

BAY-677 Biochemical – Cat# MBS8400500

Product References and Citations for BAY-677 biochemical

https://pubchem.ncbi.nlm.nih.gov/compound/68944900

Other Notes

Small volumes of BAY-677 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for BAY-677 purchase

MBS8400500 is a biochemical targeting BAY-677.
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