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R-7050

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8400503

R-7050 is a cell-permeable inhibitor of signaling through the TNFalpha receptor (TNFalphaR) complex. It blocks the formation of signal-initiating complexes that consist of TNFalpha receptor (TNFalphaR) I, TNFalphaR associated death domain protein (TRADD) and… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
R-7050, Biochemical
Full Product Name
R-7050
Product Gene Name
R-7050 biochemical
Product Synonym Names
TNF-alpha Antagonist III; 8-chloro-4-phenylsulfanyl-1-(trifluoromethyl)-[1, 2, 4]triazolo[4, 3-a]quinoxaline; 8-chloro-1-(trifluoromethyl)[1, 2, 4]triazolo[4, 3-a]quinoxalin-4-yl phenyl sulfide
Form/Format
Beige to Yellow Solid
Purity/Purification
>=98%
Specificity
An inhibitor of signaling through the TNFalpha receptor complex
Preparation and Storage
Store at -20 degree C
Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Shelf Life: Est.~36 months
Country of Origin: USA
Molecular Weight
380.77
Solubilities
~10mg/ml in DMF; ~1mg/ml in DMSO
Molecular Formula
C??H?ClF?N?S
InChi
InChI=1S/C16H8ClF3N4S/c17-9-6-7-11-12(8-9)24-13(22-23-15(24)16(18; 19)20)14(21-11)25-10-4-2-1-3-5-10/h1-8H
InChi Key
SUUMKHOVGVYGOP-UHFFFAOYSA-N
SMILES
C1=CC=C(C=C1)SC2=NC3=C(C=C(C=C3)Cl)N4C2=NN=C4C(F)(F)F
CAS Number
303997-35-5
MDL Number
MFCD00140737
PubChem CID
1486608

Product Categories/Family for R-7050 biochemical

Web Categories; Enzyme Inhibitors; Enzyme Inhibitors (A-Z); Biochemicals; Biochemicals (A-Z); Immunology; Inflammation; Neuroscience; Neuroprotective agents

Structure of R-7050 biochemical

R-7050 Biochemical – Cat# MBS8400503

Product References and Citations for R-7050 biochemical

https://pubchem.ncbi.nlm.nih.gov/compound/1486608

Other Notes

Small volumes of R-7050 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for R-7050 purchase

MBS8400503 is a biochemical targeting R-7050.
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