• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

LDN-193189

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8400507

LDN-193189 inhibits the activity of the Bone Morphogenetic Protein (BMP) type I receptors ALK2 and ALK3 with IC50 values of 5nM and 30nM respectively and shows weaker effects on activin and the TGF-beta type I receptors ALK4, ALK5 and ALK7 (IC50>= 500nM). It… More details

DISCONTINUED
Click here to view our similar product(s) OR click here to contact our technical support team for suitable replacement.
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Product Name
LDN-193189, Biochemical
Full Product Name
LDN-193189
Product Gene Name
LDN-193189 biochemical
Product Synonym Names
4-[6-(4-piperazin-1-ylphenyl)pyrazolo[1, 5-a]pyrimidin-3-yl]quinoline, DM-3189
Form/Format
Light yellow to yellow powder
Purity/Purification
>=98%
Specificity
An inhibitor of BMP receptor 1
Preparation and Storage
Store at -20 degree C
Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Shipping: Gel Pack
Shelf Life: Est.~36 months
Country of Origin: USA
Molecular Weight
406.5
Solubilities
0.2mg/ml in ethanol (may need warming and sonication)
Molecular Formula
C??H??N?
InChi
InChI=1S/C25H22N6/c1-2-4-24-22(3-1)21(9-10-27-24)23-16-29-31-17-19(15-28-25(23)31)18-5-7-20(8-6-18)30-13-11-26-12-14-30/h1-10; 15-17; 26H; 11-14H2
InChi Key
CDOVNWNANFFLFJ-UHFFFAOYSA-N
SMILES
C1CN(CCN1)C2=CC=C(C=C2)C3=CN4C(=C(C=N4)C5=CC=NC6=CC=CC=C56)N=C3
CAS Number
1062368-24-4
MDL Number
MFCD17169988
PubChem CID
25195294

Product Categories/Family for LDN-193189 biochemical

Web Categories; Enzyme Inhibitors; BMP Inhibitors; Biochemicals; Biochemicals (A-Z); Stem Cell Research Tools; Stem Cell Fate Regulators; Stem Cell Fate Regulators (A-Z); Anticancer Agents; Enzyme Inhibitors (A-Z); Cancer Research; Differentiation; Aging

Structure of LDN-193189 biochemical

LDN-193189 Biochemical – Cat# MBS8400507

Product References and Citations for LDN-193189 biochemical

https://pubchem.ncbi.nlm.nih.gov/compound/25195294

Other Notes

Small volumes of LDN-193189 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for LDN-193189 purchase

MBS8400507 is a biochemical targeting LDN-193189.
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000