Rabbit Anti-LDHA Polyclonal Antibody – Cat# MBS840153

LDHA Antibody – Rabbit Polyclonal

Name: LDHA Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS840153
Price: 375 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS840153

Polyclonal Antibody to detect LDHA in human samplesBackground: L-Lactate dehydrogenase A chain (LDHA) is a member of the LDH/MDH superfamily and LDH family. It catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic… More details

DISCONTINUED
Click here to view our similar product(s) OR click here to contact our technical support team for suitable replacement.

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

LDHA, Polyclonal Antibody

Full Product Name

LDHA Antibody (CT)

Product Gene Name

anti-LDHA antibody

Product Synonym Names

LDHA; L-lactate dehydrogenase A chain; Cell proliferation-inducing gene 19 protein; LDH muscle subunit; Renal carcinoma antigen NY-REN-59.

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human. Predicted cross reactivity with Monkey samples.

Form/Format

100 ul of antibody in PBS with 0.09% (W/V) sodium azide
Appearance: Colorless liquid

Purity/Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Preparation and Storage

At -20 degree C
Shelf Life: 12 months

Molecular Weight

26,712 Da

OMIM

150000

3D Structure

ModBase 3D Structure for P00338

Immunogen

This LDHA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 204-232 amino acids from the C-terminal region of human LDHA.

Positive Control

Western blot: MDA-MB231 cell lysate, IHC: human hepatocarcinoma, IF: A375 cells

Handling

The antibody solution should be gently mixed before use.

Product Categories/Family for anti-LDHA antibody

Antibodies & Supporting Tools; Antibodies for Metabolic Processes (NEW) Diabetes; Obesity & Metabolic Syndrome; Antibodies (NEW) Antibodies & Supporting Tools; Primary Antibodies (A-Z)

Applications Tested/Suitable for anti-LDHA antibody

Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Application Notes for anti-LDHA antibody

Western blot: ~1:1000, IHC: ~1:10-1:50, IF: ~1:10-1:50.

Other Notes

Small volumes of anti-LDHA antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for LDHA purchase

MBS840153 is an antibody targeting LDHA. Also known as LDHA Antibody (CT). Reactive in Human. Predicted cross reactivity with Monkey samples.. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for LDHA. It may not necessarily be applicable to this product.

NCBI GI #

207028494

NCBI GeneID

3939

NCBI Accession #

NP_001128711.1

UniProt Primary Accession #

P00338

UniProt Secondary Accession #

Q53G53; Q6IBM7; Q6ZNV1; Q9UDE8; Q9UDE9; B4DKQ2; B7Z5E3; D3DQY3; F8W819

UniProt Related Accession #

P00338

GenBank Nucleotide #

NM_001135239.1

NCBI Official Full Name

L-lactate dehydrogenase A chain isoform 2

NCBI Official Synonym Full Names

lactate dehydrogenase A

NCBI Official Symbol

LDHA

NCBI Official Synonym Symbols

LDH1; LDHM; GSD11; PIG19; HEL-S-133P

UniProt Protein Name

L-lactate dehydrogenase A chain

UniProt Synonym Protein Names

Cell proliferation-inducing gene 19 protein; LDH muscle subunit; LDH-M; Renal carcinoma antigen NY-REN-59

Protein Family

L-lactate dehydrogenase

UniProt Gene Name

LDHA

UniProt Synonym Gene Names

LDH-A; LDH-M

UniProt Entry Name

LDHA_HUMAN

NCBI Protein Information

L-lactate dehydrogenase A chain

NCBI Summary for LDHA

The protein encoded by this gene catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. The protein is found predominantly in muscle tissue and belongs to the lactate dehydrogenase family. Mutations in this gene have been linked to exertional myoglobinuria. Multiple transcript variants encoding different isoforms have been found for this gene. The human genome contains several non-transcribed pseudogenes of this gene. [provided by RefSeq, Sep 2008]

UniProt Comments for LDHA

LDH-A: Homotetramer. Belongs to the LDH/MDH superfamily. LDH family. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Carbohydrate Metabolism - propanoate; EC 1.1.1.27; Carbohydrate Metabolism - glycolysis and gluconeogenesis; Amino Acid Metabolism - cysteine and methionine; Oxidoreductase; Carbohydrate Metabolism - pyruvate; Apoptosis

Chromosomal Location of Human Ortholog: 11p15.4

Cellular Component: membrane; mitochondrion; nucleus; cytosol

Molecular Function: protein binding; L-lactate dehydrogenase activity

Biological Process: cellular metabolic process; substantia nigra development; glycolysis; cellular response to extracellular stimulus; cellular carbohydrate metabolic process; pyruvate metabolic process

Disease: Glycogen Storage Disease Xi

Research Articles on LDHA

1. LDHA expression is elevated in gastric cancer cells and antagonism with oxamic acid inhibited cell proliferation and migration.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-LDHA antibody

Reference Product	PubMed Publications
HIF1A antibody	>35 publications with LDHA and HIF1A
JUN antibody	>27 publications with LDHA and JUN
MYC antibody	>18 publications with LDHA and MYC
PKM antibody	>5 publications with LDHA and PKM
UBC antibody	>3 publications with LDHA and UBC
EP300 antibody	>1 publications with LDHA and EP300
ARNT antibody	>1 publications with LDHA and ARNT
ACLY antibody	>1 publications with LDHA and ACLY

Pathways associated with anti-LDHA antibody

Products by Pathway	Pathway Diagram
Biosynthesis Of Antibiotics Pathway antibodies	Biosynthesis Of Antibiotics Pathway Diagram
Central Carbon Metabolism In Cancer Pathway antibodies	Central Carbon Metabolism In Cancer Pathway Diagram
Central Carbon Metabolism In Cancer Pathway antibodies	Central Carbon Metabolism In Cancer Pathway Diagram
Cysteine And Methionine Metabolism Pathway antibodies	Cysteine And Methionine Metabolism Pathway Diagram
Cysteine And Methionine Metabolism Pathway antibodies	Cysteine And Methionine Metabolism Pathway Diagram
Glucagon Signaling Pathway antibodies	Glucagon Signaling Pathway Diagram
Glucagon Signaling Pathway antibodies	Glucagon Signaling Pathway Diagram
Glycolysis / Gluconeogenesis Pathway antibodies	Glycolysis / Gluconeogenesis Pathway Diagram
Glycolysis / Gluconeogenesis Pathway antibodies	Glycolysis / Gluconeogenesis Pathway Diagram
Glycolysis And Gluconeogenesis Pathway antibodies	Glycolysis And Gluconeogenesis Pathway Diagram

Diseases associated with anti-LDHA antibody

Disease Name	Pubmed Publications
Carcinoma, Hepatocellular Antibodies	>10 publications with LDHA and Carcinoma, Hepatocellular
Liver Diseases Antibodies	>9 publications with LDHA and Liver Diseases
Breast Neoplasms Antibodies	>9 publications with LDHA and Breast Neoplasms
Brain Diseases Antibodies	>8 publications with LDHA and Brain Diseases
Lactate dehydrogenase deficiency type A Antibodies	>8 publications with LDHA and Lactate dehydrogenase deficiency type A
Cardiovascular Diseases Antibodies	>7 publications with LDHA and Cardiovascular Diseases
Liver Neoplasms Antibodies	>7 publications with LDHA and Liver Neoplasms
Kidney Diseases Antibodies	>6 publications with LDHA and Kidney Diseases
Cell Transformation, Neoplastic Antibodies	>6 publications with LDHA and Cell Transformation, Neoplastic
Lung Neoplasms Antibodies	>6 publications with LDHA and Lung Neoplasms

Organs/Tissues associated with anti-LDHA antibody

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>38 publications with LDHA and Blood
Muscle Antibodies	>22 publications with LDHA and Muscle
Vascular Antibodies	>21 publications with LDHA and Vascular
Liver Antibodies	>21 publications with LDHA and Liver
Testis Antibodies	>19 publications with LDHA and Testis
Brain Antibodies	>18 publications with LDHA and Brain
Heart Antibodies	>11 publications with LDHA and Heart
Kidney Antibodies	>10 publications with LDHA and Kidney
Lung Antibodies	>10 publications with LDHA and Lung
Bone Antibodies	>9 publications with LDHA and Bone