Rabbit Anti-CX3CL1 Polyclonal Antibody – Cat# MBS840223

Fractalkine (CX3CL1) Antibody – Rabbit Polyclonal

Name: CX3CL1 Antibody; Polyclonal; Rabbit; Human/Mouse/Rat-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS840223
Price: 215 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS840223

Background: Fractalkine, also known as neurotactin, is a membrane-bound CX3C Chemokine. The mature protein is part of a 397-amino acid precursor and consists of a chemokine domain of 76 amino acids, a mucin stalk of 241 amino acids, a putative transmembrane… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

Fractalkine (CX3CL1), Polyclonal Antibody

Full Product Name

Fractalkine Antibody

Product Gene Name

anti-CX3CL1 antibody

Product Synonym Names

Fractalkine; C-X3-C motif chemokine 1; Neurotactin; CX3C membrane-anchored chemokine; Small-inducible cytokine D1

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Form/Format

100 ug (0.5 mg/ml) affinity purified rabbit anti-Fractalkine polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.
Appearance: Colorless liquid

Purity/Purification

Affinity purified

Concentration

0.5 mg/ml (lot specific)

Preparation and Storage

At -20 degree C
Shelf Life: 12 months

Molecular Weight

42,203 Da

OMIM

601880

Immunogen

E. coli-expressed recombinant human Fractalkine

Handling

The antibody solution should be gently mixed before use.

Applications Tested/Suitable for anti-CX3CL1 antibody

Western Blot (WB), Immunocytochemistry (ICC), Immunoprecipitation (IP)

Application Notes for anti-CX3CL1 antibody

Western blot analysis (0.5-4 ug/ml). Per researcher's feedback, it can also be used in immunoprecipitation (4-8 ug/ml), and Immunohistochemistry (10-20 ug/ml). However, the optimal conditions should be determined individually.

Other Notes

Small volumes of anti-CX3CL1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CX3CL1 purchase

MBS840223 is an antibody targeting CX3CL1. Also known as Fractalkine Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for CX3CL1. It may not necessarily be applicable to this product.

NCBI GI #

62087654

NCBI GeneID

6376

NCBI Accession #

BAD92274

UniProt Secondary Accession #

O00672

UniProt Related Accession #

P78423

NCBI Official Full Name

chemokine (C-X3-C motif) ligand 1 variant, partial

NCBI Official Synonym Full Names

chemokine (C-X3-C motif) ligand 1

NCBI Official Symbol

CX3CL1

NCBI Official Synonym Symbols

NTN; NTT; CXC3; CXC3C; SCYD1; ABCD-3; C3Xkine; fractalkine; neurotactin

UniProt Protein Name

Fractalkine

UniProt Synonym Protein Names

C-X3-C motif chemokine 1; CX3C membrane-anchored chemokine; Neurotactin; Small-inducible cytokine D1

Protein Family

Fractalkine

UniProt Gene Name

CX3CL1

UniProt Synonym Gene Names

FKN; NTT; SCYD1

UniProt Entry Name

X3CL1_HUMAN

NCBI Protein Information

fractalkine

UniProt Comments for CX3CL1

CX3CL1: The soluble form is chemotactic for T-cells and monocytes, but not for neutrophils. The membrane-bound form promotes adhesion of those leukocytes to endothelial cells. May play a role in regulating leukocyte adhesion and migration processes at the endothelium. Binds to CX3CR1. Belongs to the intercrine delta family.

Protein type: Motility/polarity/chemotaxis; Membrane protein, integral

Chromosomal Location of Human Ortholog: 16q13

Cellular Component: extracellular space; cell surface; integral to membrane; plasma membrane; extracellular region

Molecular Function: protein binding; chemokine activity; receptor binding

Biological Process: neutrophil chemotaxis; positive regulation of transforming growth factor-beta1 production; cytokine and chemokine mediated signaling pathway; leukocyte chemotaxis; defense response; chemotaxis; angiogenesis involved in wound healing; leukocyte adhesive activation; macrophage chemotaxis; positive regulation of angiogenesis; positive regulation of calcium-independent cell-cell adhesion; immune response; cell adhesion; lymphocyte chemotaxis; positive regulation of inflammatory response

Research Articles on CX3CL1

1. Data indicate that metalloprotease ADAM10 has limited interaction with CX3CL1 chemokine on the surface of umbilical vein endothelial cell.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-CX3CL1 antibody

Reference Product	PubMed Publications
CX3CR1 antibody	>502 publications with CX3CL1 and CX3CR1
CCR2 antibody	>61 publications with CX3CL1 and CCR2
CCR5 antibody	>37 publications with CX3CL1 and CCR5
CXCR3 antibody	>30 publications with CX3CL1 and CXCR3
CCR1 antibody	>19 publications with CX3CL1 and CCR1
CCR7 antibody	>13 publications with CX3CL1 and CCR7
CXCR2 antibody	>13 publications with CX3CL1 and CXCR2
CCR3 antibody	>13 publications with CX3CL1 and CCR3
CXCR1 antibody	>8 publications with CX3CL1 and CXCR1

Diseases associated with anti-CX3CL1 antibody

Disease Name	Pubmed Publications
Inflammation Antibodies	>349 publications with CX3CL1 and Inflammation
Necrosis Antibodies	>182 publications with CX3CL1 and Necrosis
Cardiovascular Diseases Antibodies	>154 publications with CX3CL1 and Cardiovascular Diseases
Atherosclerosis Antibodies	>95 publications with CX3CL1 and Atherosclerosis
Lung Diseases Antibodies	>67 publications with CX3CL1 and Lung Diseases
Pain Antibodies	>62 publications with CX3CL1 and Pain
Kidney Diseases Antibodies	>57 publications with CX3CL1 and Kidney Diseases
Heart Diseases Antibodies	>50 publications with CX3CL1 and Heart Diseases
Liver Diseases Antibodies	>50 publications with CX3CL1 and Liver Diseases
Myocardial Ischemia Antibodies	>42 publications with CX3CL1 and Myocardial Ischemia

Organs/Tissues associated with anti-CX3CL1 antibody

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>196 publications with CX3CL1 and Brain
Muscle Antibodies	>94 publications with CX3CL1 and Muscle
Kidney Antibodies	>86 publications with CX3CL1 and Kidney
Lung Antibodies	>85 publications with CX3CL1 and Lung
Heart Antibodies	>67 publications with CX3CL1 and Heart
Liver Antibodies	>64 publications with CX3CL1 and Liver
Nerve Antibodies	>53 publications with CX3CL1 and Nerve
Skin Antibodies	>42 publications with CX3CL1 and Skin
Intestine Antibodies	>33 publications with CX3CL1 and Intestine
Eye Antibodies	>27 publications with CX3CL1 and Eye