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CCR3 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS840280

Background: Chemokines play important roles in inflammation and critical for the recruitment of effector immune cells to sites of infection. Chemokines activate leukocytes by binding to G protein coupled receptors. The ever-growing chemokine receptor subtypes… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
CCR3, Polyclonal Antibody
Full Product Name
CCR3 Antibody
Product Gene Name
anti-CCR3 antibody
Product Synonym Names
CMKBR3; CKR3; CD193; CC-CKR-3; C CKR-3; CC-CKR-3; CCR-3; CCR3
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
100 ug (0.5 mg/ml) Protein G purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.
Appearance: Colorless liquid
Purity/Purification
Affinity purified
Concentration
0.5 mg/ml (lot specific)
Preparation and Storage
At -20 degree C
Shelf Life: 12 months
Molecular Weight
41,643 Da
Immunogen
Synthetic peptide surrounding amino acid 332 of rat CCR3
Handling
The antibody solution should be gently mixed before use.
Applications Tested/Suitable for anti-CCR3 antibody
Western Blot (WB)
Application Notes for anti-CCR3 antibody
Western blotting (0.5-4 ug/ml). However, the optimal concentrations should be determined individually.

Testing Data of anti-CCR3 antibody

Rabbit Anti-CCR3 Polyclonal Antibody – Cat# MBS840280

Other Notes

Small volumes of anti-CCR3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CCR3 purchase

MBS840280 is an antibody targeting CCR3. Also known as CCR3 Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for CCR3. It may not necessarily be applicable to this product.

NCBI GI #
16758844
NCBI GeneID
117027
NCBI Accession #
NP_446410
UniProt Secondary Accession #
O55169
UniProt Related Accession #
O54814
GenBank Nucleotide #
NM_053958.1
NCBI Official Full Name
C-C chemokine receptor type 3
NCBI Official Synonym Full Names
chemokine (C-C motif) receptor 3
NCBI Official Symbol
Ccr3
NCBI Official Synonym Symbols
Cmkbr3
UniProt Protein Name
C-C chemokine receptor type 3
UniProt Synonym Protein Names
CD_antigen: CD193
Protein Family
C-C chemokine receptor
UniProt Gene Name
Ccr3
UniProt Synonym Gene Names
Cmkbr3; C-C CKR-3; CC-CKR-3; CCR-3; CCR3; CKR3
UniProt Entry Name
CCR3_RAT
NCBI Protein Information
C-C chemokine receptor type 3

NCBI Summary for CCR3

chemokine receptor; may have a role in inflammation and HIV infection [RGD, Feb 2006]

UniProt Comments for CCR3

CCR3: Receptor for a C-C type chemokine. Binds to eotaxin, eotaxin-3, MCP-3, MCP-4, RANTES and MIP-1 delta. Subsequently transduces a signal by increasing the intracellular calcium ions level. Alternative coreceptor with CD4 for HIV-1 infection. Belongs to the G-protein coupled receptor 1 family.

Protein type: Receptor, cytokine; GPCR, family 1; Membrane protein, integral; Motility/polarity/chemotaxis; Receptor, GPCR; Membrane protein, multi-pass

Cellular Component: extracellular space; integral to membrane; plasma membrane; endosome

Molecular Function: C-C chemokine receptor activity; chemokine receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway; positive regulation of angiogenesis; mast cell chemotaxis; eosinophil chemotaxis; positive regulation of endothelial cell proliferation; inflammatory response; chemotaxis
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Research Articles on CCR3

1. CCR3 plays no role in choroidal neovascularization development.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-CCR3 antibody

 Reference Product  PubMed Publications
 Ccl11 antibody  >334 publications with CCR3 and Ccl11
 Cxcr4 antibody  >299 publications with CCR3 and Cxcr4
 Ccl5 antibody  >199 publications with CCR3 and Ccl5
 Ccl2 antibody  >104 publications with CCR3 and Ccl2
 Cxcl12 antibody  >38 publications with CCR3 and Cxcl12
 Ccl12 antibody  >7 publications with CCR3 and Ccl12
 Fpr2 antibody  >4 publications with CCR3 and Fpr2

Diseases associated with anti-CCR3 antibody

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >370 publications with CCR3 and Inflammation
 Asthma Antibodies  >248 publications with CCR3 and Asthma
 Lung Diseases Antibodies  >202 publications with CCR3 and Lung Diseases
 Respiratory Hypersensitivity Antibodies  >176 publications with CCR3 and Respiratory Hypersensitivity
 HIV Infections Antibodies  >123 publications with CCR3 and HIV Infections
 Necrosis Antibodies  >82 publications with CCR3 and Necrosis
 Dermatitis, Atopic Antibodies  >43 publications with CCR3 and Dermatitis, Atopic
 Vascular Diseases Antibodies  >34 publications with CCR3 and Vascular Diseases
 Fibrosis Antibodies  >23 publications with CCR3 and Fibrosis
 Hyperplasia Antibodies  >22 publications with CCR3 and Hyperplasia
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