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ROBO4 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS840330

Background: ROBO4 contains two fibronectin type-III domains and two Ig-like C2-type domains. ROBO4 is predominantly expressed in vascular endothelium and is considered important for vascular development. ROBO4 is a receptor for Slit proteins and may mediate… More details

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Sample Manual Insert View PDF
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Testing Data View PDF
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Product Overview

Product Name
ROBO4, Polyclonal Antibody
Full Product Name
ROBO4 Antibody
Product Gene Name
Product Synonym Names
UNQ421/PRO3674; ECSM4; FLJ20798; MGC133352; MGC133353; MRB
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
0.5mg/ml in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 5 mM EDTA and 0.03% proclin
Purity/Purification
Affinity purified
Preparation and Storage
Store at -20°C. For long term, store at -70°C. Avoid repeated freeze/thawcycles
3D Structure
ModBase 3D Structure for Q80W87
Immunogen
Synthetic peptide surrounding amino acid 322 of rat ROBO4
Handling
The antibody solution should be gently mixed before use.
Applications Tested/Suitable for anti-ROBO4 antibody
The antibody can be used in Western Blot (1-4 ?g/ml).However, the optimal concentrations should be determined individually. Blocking peptide (MBS843949) is available separately.
Application Notes for anti-ROBO4 antibody
Western blotting (1-4 ug/ml). However, the optimal conditions should be determined individually. The antibody detects the ROBO4 band in human samples.

Testing Data of anti-ROBO4 antibody

Rabbit Anti-ROBO4 Polyclonal Antibody – Cat# MBS840330

Other Notes

Small volumes of anti-ROBO4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ROBO4 purchase

MBS840330 is an antibody targeting ROBO4. Also known as ROBO4 Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for ROBO4. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
roundabout homolog 4
NCBI Official Synonym Full Names
roundabout guidance receptor 4
NCBI Official Symbol
Robo4
UniProt Protein Name
Roundabout homolog 4
Protein Family
UniProt Gene Name
Robo4
UniProt Entry Name
ROBO4_RAT
NCBI Protein Information
roundabout homolog 4

UniProt Comments for ROBO4

ROBO4: Receptor for Slit proteins, at least for SLIT2, and seems to be involved in angiogenesis and vascular patterning. May mediate the inhibition of primary endothelial cell migration by Slit proteins. Belongs to the immunoglobulin superfamily. ROBO family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted, signal peptide; Secreted

Cellular Component: external side of plasma membrane

Molecular Function: receptor activity

Biological Process: angiogenesis; cell differentiation; negative regulation of cell migration
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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