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Lymphotactin (XCL1) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS840405

Background: Lymphotactin is the only C chemokine so far identified which has a single cysteine residue near the amino terminus. It has 114 amino acids with a 22 amino acids signal peptide. It is produced in activated CD8+ T cells and NK cells. Lymphotactin… More details

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Product Overview

Product Name
Lymphotactin (Xcl1), Polyclonal Antibody
Full Product Name
Lymphotactin Antibody
Product Gene Name
anti-Xcl1 antibody
Product Synonym Names
C motif chemokine 1; Cytokine SCM-1; Small-inducible cytokine C1
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Rat
Form/Format
100 ug (0.5 mg/ml) affinity purified rabbit anti-rat Lymphotactin polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA, 0.02% thimerosal.
Appearance: Colorless liquid
Purity/Purification
Affinity purified
Concentration
0.5 mg/ml (lot specific)
Preparation and Storage
At -20 degree C
Shelf Life: 12 months
Molecular Weight
12,370 Da
Immunogen
E. coli-expressed rat lymphotactin (a.a. 1-92)
Handling
The antibody solution should be gently mixed before use.
Applications Tested/Suitable for anti-Xcl1 antibody
Western Blot (WB), Immunoprecipitation (IP), Neutralization
Application Notes for anti-Xcl1 antibody
Western blot analysis (0.5-4 ug/ml) and immunoprecipitation (4-8 ug/ml). However, the optimal conditions should be determined individually.

Testing Data of anti-Xcl1 antibody

Rabbit Anti-XCL1 Polyclonal Antibody – Cat# MBS840405

Other Notes

Small volumes of anti-Xcl1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Xcl1 purchase

MBS840405 is an antibody targeting Xcl1. Also known as Lymphotactin Antibody. Reactive in Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for Xcl1. It may not necessarily be applicable to this product.

NCBI GI #
19705461
NCBI GeneID
171371
NCBI Accession #
NP_599188
UniProt Related Accession #
P51672
GenBank Nucleotide #
NM_134361.1
NCBI Official Full Name
lymphotactin
NCBI Official Synonym Full Names
chemokine (C motif) ligand 1
NCBI Official Symbol
Xcl1
NCBI Official Synonym Symbols
Ltn; Scyc1
UniProt Protein Name
Lymphotactin
UniProt Synonym Protein Names
C motif chemokine 1; Cytokine SCM-1; Small-inducible cytokine C1
Protein Family
Lymphotactin
UniProt Gene Name
Xcl1
UniProt Synonym Gene Names
Ltn; Scyc1
UniProt Entry Name
XCL1_RAT
NCBI Protein Information
lymphotactin

NCBI Summary for Xcl1

mouse homolog is a cytokine with chemotactic activity for lymphocytes but not for monocytes or neutrophils [RGD, Feb 2006]

UniProt Comments for Xcl1

XCL1: Chemotactic activity for lymphocytes but not for monocytes or neutrophils. Belongs to the intercrine gamma family.

Protein type: Secreted; Motility/polarity/chemotaxis; Secreted, signal peptide

Cellular Component: extracellular space; cell; intracellular; cytosol

Molecular Function: protein homodimerization activity; chemokine activity; chemokine receptor binding

Biological Process: positive regulation of T cell mediated cytotoxicity; negative regulation of transcription factor activity; response to virus; positive regulation of T cell cytokine production; positive regulation of leukocyte chemotaxis; negative regulation of T cell cytokine production; chemotaxis; positive regulation of interleukin-10 production; negative regulation of interleukin-2 production; cell-cell signaling; release of sequestered calcium ion into cytosol; negative regulation of interferon-gamma production; regulation of inflammatory response; immune response; positive regulation of release of sequestered calcium ion into cytosol; negative regulation of transcription, DNA-dependent
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Research Articles on Xcl1

1. biology of vXCL1 offers an interesting opportunity to study the role of XCL1 and XCR1(+) DC in the cross-presentation of viral antigens

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-Xcl1 antibody

 Reference Product  PubMed Publications
 Xcr1 antibody  >36 publications with Xcl1 and Xcr1
 Ccl9 antibody  >2 publications with Xcl1 and Ccl9
 Ccl6 antibody  >1 publications with Xcl1 and Ccl6

Pathways associated with anti-Xcl1 antibody

 Products by Pathway  Pathway Diagram
 Chemokine Receptors Bind Chemokines Pathway antibodies  Chemokine Receptors Bind Chemokines Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 G Alpha (q) Signalling Events Pathway antibodies  G Alpha (q) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 Gastrin-CREB Signalling Pathway Via PKC And MAPK antibodies  Gastrin-CREB Signalling Pathway Via PKC And MAPK Diagram
 Peptide Ligand-binding Receptors Pathway antibodies  Peptide Ligand-binding Receptors Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram

Diseases associated with anti-Xcl1 antibody

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >28 publications with Xcl1 and Inflammation
 Disease Models, Animal Antibodies  >18 publications with Xcl1 and Disease Models, Animal
 Necrosis Antibodies  >18 publications with Xcl1 and Necrosis
 Neoplasms, Experimental Antibodies  >15 publications with Xcl1 and Neoplasms, Experimental
 Lung Diseases Antibodies  >12 publications with Xcl1 and Lung Diseases
 Nervous System Diseases Antibodies  >7 publications with Xcl1 and Nervous System Diseases
 Multiple Myeloma Antibodies  >5 publications with Xcl1 and Multiple Myeloma
 Eye Diseases Antibodies  >4 publications with Xcl1 and Eye Diseases
 Liver Neoplasms Antibodies  >3 publications with Xcl1 and Liver Neoplasms
 Kidney Diseases Antibodies  >3 publications with Xcl1 and Kidney Diseases

Organs/Tissues associated with anti-Xcl1 antibody

 Organ/Tissue Name  Pubmed Publications
 Ovary Antibodies  >1 publications with Xcl1 and Ovary
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