Rabbit Anti-CCR4 Polyclonal Antibody – Cat# MBS840622

CCR4 Antibody – Rabbit Polyclonal

Name: CCR4 Antibody; Polyclonal; Rabbit; Human/Mouse-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS840622
Price: 215 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS840622

Background: CCR4 is a chemokine receptor and is preferentially expressed on type 2 helper T (Th2-type) cells. In contrast to other chemokine receptors, the expression of CCR4 and CCR8 on Th2 cells is transiently increased following TCR and CD28 engagement.… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

CCR4, Polyclonal Antibody

Full Product Name

CCR4 Antibody

Product Gene Name

anti-CCR4 antibody

Product Synonym Names

C-C chemokine receptor 4; CCR 4; chemokine C C motif receptor 4; C-C CKR-4; K5-5

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human, Mouse, Dog

Form/Format

100 ug (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.
Appearance: Colorless liquid

Purity/Purification

Affinity purified

Concentration

0.5 mg/ml (lot specific)

Preparation and Storage

At -20 degree C
Shelf Life: 12 months

Molecular Weight

94,670 Da

Immunogen

Synthetic peptide surrounding amino acid 32 of human CCR4

Handling

The antibody solution should be gently mixed before use.

Applications Tested/Suitable for anti-CCR4 antibody

Western Blot (WB)

Application Notes for anti-CCR4 antibody

Western blotting (2-6 ug/ml). However, the optimal concentrations should be determined individually.

Other Notes

Small volumes of anti-CCR4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CCR4 purchase

MBS840622 is an antibody targeting CCR4. Also known as CCR4 Antibody. Reactive in Human, Mouse, Dog. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for CCR4. It may not necessarily be applicable to this product.

NCBI GI #

261567

NCBI Accession #

AAB24455.1

UniProt Secondary Accession #

D6VPJ7

NCBI Official Full Name

CCR4

UniProt Protein Name

Glucose-repressible alcohol dehydrogenase transcriptional effector

UniProt Synonym Protein Names

Carbon catabolite repressor protein 4; Cytoplasmic deadenylase

Protein Family

C-C chemokine receptor

UniProt Gene Name

CCR4

UniProt Entry Name

CCR4_YEAST

UniProt Comments for CCR4

Acts as catalytic component of the CCR4-NOT core complex, which in the nucleus seems to be a general transcription factor, and in the cytoplasm the major mRNA deadenylase involved in mRNA turnover. CCR4 has 3'-5' RNase activity with a strong preference for polyadenylated substrates and also low exonuclease activity towards single-stranded DNA. Discovered because of its role in the control of ADH2 gene expression. It is required for the expression of genes involved in non-fermentative growth and it mediates or is required for the action of the SPT6 and SPT10 genes.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.