Rabbit Anti-TOM 40 Polyclonal Antibody – Cat# MBS840642

TOM 40 Antibody – Rabbit Polyclonal

Name: TOM 40 Antibody; Polyclonal; Rabbit; Human/Mouse/Rat-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS840642
Price: 215 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS840642

Background: Translocase of the mitochondria Outer Membrane (TOM) is essential for protein import into mitochondria. TOM40 is synthesized in the cytosol and contains information for its mitochondrial targeting and assembly. It is delivered to the mitochondria… More details

DISCONTINUED
Click here to view our similar product(s) OR click here to contact our technical support team for suitable replacement.

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

Tom 40, Polyclonal Antibody

Full Product Name

Tom 40 Antibody

Product Gene Name

anti-Tom 40 antibody

Product Synonym Names

C19orf1; D19S1177E; PER-EC1; PEREC1; TOM40; p38.5

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Form/Format

100 ug (0.5 mg/ml) purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA and 0.01% thimerosal.
Appearance: Colorless liquid

Purity/Purification

Affinity purified

Concentration

0.5 mg/ml (lot specific)

Preparation and Storage

At -20 degree C
Shelf Life: 12 months

Molecular Weight

34,441 Da

OMIM

608061

3D Structure

ModBase 3D Structure for O96008

Immunogen

Synthetic peptide surrounding amino acid 339 of human TOM40

Handling

The antibody solution should be gently mixed before use.

Applications Tested/Suitable for anti-Tom 40 antibody

Western Blot (WB)

Application Notes for anti-Tom 40 antibody

Western blotting (0.5-4 ug/ml). However, the optimal concentrations should be determined individually. Blocking peptide is available separately. The antibody recognizes TOM40 in samples of human, mouse and rat origins. Reactivity to other species has not been tested.

Other Notes

Small volumes of anti-Tom 40 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Tom 40 purchase

MBS840642 is an antibody targeting Tom 40. Also known as Tom 40 Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for Tom 40. It may not necessarily be applicable to this product.

NCBI GI #

193083120

NCBI GeneID

10452

NCBI Accession #

NP_001122388.1

UniProt Primary Accession #

O96008

UniProt Secondary Accession #

Q86VW4; Q8WY09; Q8WY10; Q8WY11; Q9BR95

UniProt Related Accession #

O96008

GenBank Nucleotide #

NM_001128916.1

NCBI Official Full Name

mitochondrial import receptor subunit TOM40 homolog

NCBI Official Synonym Full Names

translocase of outer mitochondrial membrane 40 homolog (yeast)

NCBI Official Symbol

TOMM40

NCBI Official Synonym Symbols

TOM40; PEREC1; C19orf1; PER-EC1; D19S1177E

UniProt Protein Name

Mitochondrial import receptor subunit TOM40 homolog

UniProt Synonym Protein Names

Protein Haymaker; Translocase of outer membrane 40 kDa subunit homolog; p38.5

UniProt Gene Name

TOMM40

UniProt Synonym Gene Names

C19orf1; PEREC1; TOM40

UniProt Entry Name

TOM40_HUMAN

NCBI Protein Information

mitochondrial import receptor subunit TOM40 homolog

NCBI Summary for Tom 40

TOMM40 is the channel-forming subunit of the translocase of the mitochondrial outer membrane (TOM) complex that is essential for protein import into mitochondria (Humphries et al., 2005 [PubMed 15644312]).[supplied by OMIM, May 2008]

UniProt Comments for Tom 40

TOMM40: Channel-forming protein essential for import of protein precursors into mitochondria. Belongs to the Tom40 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, multi-pass; Mitochondrial

Chromosomal Location of Human Ortholog: 19q13

Cellular Component: nucleoplasm; pore complex; mitochondrial outer membrane translocase complex; mitochondrion; cytoplasm; integral to membrane; integral to mitochondrial outer membrane

Molecular Function: protein transmembrane transporter activity; porin activity

Biological Process: cellular protein metabolic process; ion transport; protein targeting to mitochondrion

Research Articles on Tom 40

1. The present study shows for the first time that TOMM40 rs157581 polymorphism may modulate regional spontaneous brain activity and related to the progression of amnestic mild cognitive impairment.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-Tom 40 antibody

Reference Product	PubMed Publications
TOMM22 antibody	>2 publications with Tom 40 and TOMM22
TOMM20 antibody	>2 publications with Tom 40 and TOMM20
TOMM70A antibody	>1 publications with Tom 40 and TOMM70A

Diseases associated with anti-Tom 40 antibody

Disease Name	Pubmed Publications
Nervous System Diseases Antibodies	>64 publications with Tom 40 and Nervous System Diseases
Brain Diseases Antibodies	>60 publications with Tom 40 and Brain Diseases
Cognition Disorders Antibodies	>14 publications with Tom 40 and Cognition Disorders
Cardiovascular Diseases Antibodies	>9 publications with Tom 40 and Cardiovascular Diseases
Memory Disorders Antibodies	>8 publications with Tom 40 and Memory Disorders
Neurobehavioral Manifestations Antibodies	>5 publications with Tom 40 and Neurobehavioral Manifestations
Inflammation Antibodies	>4 publications with Tom 40 and Inflammation
Learning Disorders Antibodies	>3 publications with Tom 40 and Learning Disorders
Hypertension Antibodies	>3 publications with Tom 40 and Hypertension
Diabetes Mellitus Antibodies	>2 publications with Tom 40 and Diabetes Mellitus

Organs/Tissues associated with anti-Tom 40 antibody

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>33 publications with Tom 40 and Brain
Blood Antibodies	>18 publications with Tom 40 and Blood
Muscle Antibodies	>4 publications with Tom 40 and Muscle
Lung Antibodies	>3 publications with Tom 40 and Lung
Prostate Antibodies	>2 publications with Tom 40 and Prostate
Eye Antibodies	>2 publications with Tom 40 and Eye
Liver Antibodies	>1 publications with Tom 40 and Liver
Mammary Gland Antibodies	>1 publications with Tom 40 and Mammary Gland
Connective Tissue Antibodies	>1 publications with Tom 40 and Connective Tissue
Uterus Antibodies	>1 publications with Tom 40 and Uterus