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Prolactin (PRL) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS840694

Background: Prolactin (also known as mammotrophin, luterotropic hormone, and lutetropin) is a neuroendocrine hormone secreted by the pituitary gland. Its primary function is to promote and maintain lactation during pregnancy and suckling. In addition,… More details

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Product Overview

Product Name
Prolactin (Prl), Polyclonal Antibody
Full Product Name
Prolactin Antibody
Product Gene Name
anti-Prl antibody
Product Synonym Names
PRL; luteotropic hormone; LTH; PRLR; PRL-R; PRL R
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Rat
Form/Format
100 ug (0.5 mg/ml) affinity purified rabbit anti-rat Prolactin polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol and 0.01% thimerosal.
Appearance: Colorless liquid
Purity/Purification
Affinity purified
Concentration
0.5 mg/ml (lot specific)
Preparation and Storage
At -20 degree C
Shelf Life: 12 months
Molecular Weight
25,753 Da
Immunogen
E. coli expressed recombinant rat Prolactin
Handling
The antibody solution should be gently mixed before use.
Applications Tested/Suitable for anti-Prl antibody
Western Blot (WB)
Application Notes for anti-Prl antibody
Western blot analysis (0.5-4 ug/ml). Recombinant rat Prolactin can be use as a positive control. However, the optimal conditions should be determined individually. Other applications have not been determined.

Testing Data of anti-Prl antibody

Rabbit Anti-PRL Polyclonal Antibody – Cat# MBS840694

Other Notes

Small volumes of anti-Prl antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Prl purchase

MBS840694 is an antibody targeting Prl. Also known as Prolactin Antibody. Reactive in Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for Prl. It may not necessarily be applicable to this product.

NCBI GI #
6981404
NCBI GeneID
24683
NCBI Accession #
NP_036761
UniProt Secondary Accession #
P70520
UniProt Related Accession #
P01237
GenBank Nucleotide #
NM_012629.1
NCBI Official Full Name
prolactin
NCBI Official Synonym Full Names
prolactin
NCBI Official Symbol
Prl
NCBI Official Synonym Symbols
PRLB; Prol; PRLSD1; Prl1a1; RNPROL; RATPRLSD1
UniProt Protein Name
Prolactin
Protein Family
Prolactin
UniProt Gene Name
Prl
UniProt Synonym Gene Names
PRL
UniProt Entry Name
PRL_RAT
NCBI Protein Information
prolactin

NCBI Summary for Prl

induces lactation; may facilitate decidual growth and placentation; promotes prostate epithelial cell proliferation [RGD, Feb 2006]

UniProt Comments for Prl

prolactin: Prolactin acts primarily on the mammary gland by promoting lactation. Belongs to the somatotropin/prolactin family.

Protein type: Secreted; Motility/polarity/chemotaxis; Cytokine; Secreted, signal peptide

Cellular Component: extracellular region; secretory granule

Molecular Function: prolactin receptor binding; hormone activity

Biological Process: response to drug; lactation; circadian rhythm; maternal behavior; positive regulation of JAK-STAT cascade; regulation of multicellular organism growth; response to lipopolysaccharide; response to organic cyclic substance; response to estradiol stimulus; cellular response to hormone stimulus; response to ethanol; ovulation cycle; regulation of JAK-STAT cascade; mammary gland development; positive regulation of cell proliferation; parturition; regulation of ossification; multicellular organismal response to stress; response to nutrient; positive regulation of epithelial cell proliferation; STAT protein nuclear translocation
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Research Articles on Prl

1. This study showe that TGF-beta and TNF-alpha antagonize the effect of each other on the expression and release of prolactin in a cell line and in obese and diabetic rats.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-Prl antibody

 Reference Product  PubMed Publications
 Prlr antibody  >362 publications with Prl and Prlr
 Jak2 antibody  >191 publications with Prl and Jak2
 Stat5a antibody  >82 publications with Prl and Stat5a
 Stat3 antibody  >63 publications with Prl and Stat3
 Stat1 antibody  >53 publications with Prl and Stat1
 Ghr antibody  >52 publications with Prl and Ghr
 Stat5b antibody  >48 publications with Prl and Stat5b
 Jak1 antibody  >10 publications with Prl and Jak1
 Gh1 antibody  >9 publications with Prl and Gh1
 Jak3 antibody  >7 publications with Prl and Jak3

Pathways associated with anti-Prl antibody

 Products by Pathway  Pathway Diagram
 Cytokine Signaling In Immune System Pathway antibodies  Cytokine Signaling In Immune System Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Jak-STAT Signaling Pathway antibodies  Jak-STAT Signaling Pathway Diagram
 Jak-STAT Signaling Pathway antibodies  Jak-STAT Signaling Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 Nuclear Signaling By ERBB4 Pathway antibodies  Nuclear Signaling By ERBB4 Pathway Diagram
 PI3K-Akt Signaling Pathway antibodies  PI3K-Akt Signaling Pathway Diagram

Diseases associated with anti-Prl antibody

 Disease Name  Pubmed Publications
 Pituitary Neoplasms Antibodies  >2041 publications with Prl and Pituitary Neoplasms
 Hyperprolactinemia Antibodies  >1535 publications with Prl and Hyperprolactinemia
 Adenoma Antibodies  >1503 publications with Prl and Adenoma
 Prolactinoma Antibodies  >688 publications with Prl and Prolactinoma
 Mental Disorders Antibodies  >610 publications with Prl and Mental Disorders
 Amenorrhea Antibodies  >428 publications with Prl and Amenorrhea
 Galactorrhea Antibodies  >319 publications with Prl and Galactorrhea
 Growth Hormone-Secreting Pituitary Adenoma Antibodies  >265 publications with Prl and Growth Hormone-Secreting Pituitary Adenoma
 Infertility, Female Antibodies  >243 publications with Prl and Infertility, Female
 Hypogonadism Antibodies  >209 publications with Prl and Hypogonadism

Organs/Tissues associated with anti-Prl antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >5156 publications with Prl and Brain
 Pituitary Gland Antibodies  >4001 publications with Prl and Pituitary Gland
 Inner Ear Antibodies  >3 publications with Prl and Inner Ear
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