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HMG2L1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS840827

Polyclonal Antibody to detect HMG2L1 in human samples. Background: High mobility group (HMG) protein 1 and 2 has been classified by DNA binding preferences and are ubiquitous non-histone components of chromatin. They bind to the minor groove of AT-rich DNA… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
HMG2L1, Polyclonal Antibody
Full Product Name
HMG2L1 polyclonal antibody
Product Gene Name
anti-HMG2L1 antibody
Product Synonym Names
HMGXB4
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
In PBS with 0.05% (W/V) sodium azide.
Appearance: Colorless liquid
Preparation and Storage
At -20 degree C
Shelf Life: 12 months
Molecular Weight
65,712 Da
OMIM
604702
3D Structure
ModBase 3D Structure for Q9UGU5
Immunogen
Polyclonal antibody raised in rabbit against human HMG2L1 (High mobility group protein 2-like 1) using two KLH conjugated synthetic peptides containing a sequence from the N-terminal and central region of the protein, respectively.
Positive Control
ELISA: Peptides.
Handling
The antibody solution should be gently mixed before use.

Product Categories/Family for anti-HMG2L1 antibody

Epigenetics; Other Epigenetics Products; Antibodies & Blocking PeptidesAntibodies & Supporting Tools; Antibodies for Epigenetics ResearchAntibodies & Supporting Tools; Primary Antibodies (A-Z)
Applications Tested/Suitable for anti-HMG2L1 antibody
ELISA (EIA)
Application Notes for anti-HMG2L1 antibody
ELISA: 1:1000.

Testing Data of anti-HMG2L1 antibody

Rabbit Anti-HMG2L1 Polyclonal Antibody – Cat# MBS840827

Other Notes

Small volumes of anti-HMG2L1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for HMG2L1 purchase

MBS840827 is an antibody targeting HMG2L1. Also known as HMG2L1 polyclonal antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for HMG2L1. It may not necessarily be applicable to this product.

NCBI GI #
51173873
NCBI GeneID
10042
NCBI Accession #
NP_001003681.1
UniProt Primary Accession #
Q9UGU5
UniProt Secondary Accession #
O75672; O75673; Q9UMT5
UniProt Related Accession #
Q9UGU5
GenBank Nucleotide #
NM_001003681.2
NCBI Official Full Name
HMG domain-containing protein 4
NCBI Official Synonym Full Names
HMG box domain containing 4
NCBI Official Symbol
HMGXB4
NCBI Official Synonym Symbols
HMG2L1; HMGBCG; THC211630
UniProt Protein Name
HMG domain-containing protein 4
UniProt Synonym Protein Names
HMG box-containing protein 4; High mobility group protein 2-like 1; Protein HMGBCG
UniProt Gene Name
HMGXB4
UniProt Synonym Gene Names
HMG2L1; HMGBCG
UniProt Entry Name
HMGX4_HUMAN
NCBI Protein Information
HMG domain-containing protein 4

NCBI Summary for HMG2L1

High mobility group (HMG) proteins are nonhistone chromosomal proteins. See HMG2 (MIM 163906) for additional information on HMG proteins.[supplied by OMIM, Nov 2010]

UniProt Comments for HMG2L1

HMG2L1: Negatively regulates Wnt/beta-catenin signaling during development.

Protein type: DNA-binding

Chromosomal Location of Human Ortholog: 22q13.1

Molecular Function: DNA binding; chromatin binding

Biological Process: chromatin remodeling; negative regulation of Wnt receptor signaling pathway; Wnt receptor signaling pathway; regulation of transcription, DNA-dependent; endosome to lysosome transport
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Research Articles on HMG2L1

1. the first evidence of this novel HMG2L1 molecule playing an important role in attenuating smooth muscle differentiation

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
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