Rabbit Anti-HDAC11 Polyclonal Antibody – Cat# MBS840833

HDAC11 Antibody – Rabbit Polyclonal

Name: HDAC11 Antibody; Polyclonal; Rabbit; Human/Mouse/Rat-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS840833
Price: 215 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS840833

Background: HDAC family are divided into two classes, I and II. Class I of the HDAC family comprises four members, HDAC-1, 2, 3, and 8. Class II of the HDAC family comprises HDAC-4, 5, 6, and 7, the molecular weights of which are all about two-fold larger… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

HDAC11, Polyclonal Antibody

Full Product Name

HDAC11 Antibody

Product Gene Name

anti-HDAC11 antibody

Product Synonym Names

HD11; Histone deacetylase 11

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Form/Format

100 ug (0.2 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.
Appearance: Colorless liquid

Purity/Purification

Affinity purified

Concentration

0.2 mg/ml (lot specific)

Preparation and Storage

At -20 degree C
Shelf Life: 12 months

Molecular Weight

33,124 Da

OMIM

607226

3D Structure

ModBase 3D Structure for Q96DB2

Immunogen

Synthetic peptide surrounding amino acid 269 of human HDAC-11

Handling

The antibody solution should be gently mixed before use.

Applications Tested/Suitable for anti-HDAC11 antibody

Western Blot (WB)

Application Notes for anti-HDAC11 antibody

Western blotting (0.5-4 ug/ml), However, the optimal concentrations should be determined individually. The antibody recognizes 39 kDa HDAC-11 of human, mouse, and rat origins

Other Notes

Small volumes of anti-HDAC11 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for HDAC11 purchase

MBS840833 is an antibody targeting HDAC11. Also known as HDAC11 Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for HDAC11. It may not necessarily be applicable to this product.

NCBI GI #

209862883

NCBI GeneID

79885

NCBI Accession #

NP_001129513.1

UniProt Primary Accession #

Q96DB2

UniProt Secondary Accession #

Q9H6I7; Q9H6X3; Q9NTC9; B4DDK1

UniProt Related Accession #

Q96DB2

GenBank Nucleotide #

NM_001136041.2

NCBI Official Full Name

histone deacetylase 11 isoform 2

NCBI Official Synonym Full Names

histone deacetylase 11

NCBI Official Symbol

HDAC11

NCBI Official Synonym Symbols

HD11

UniProt Protein Name

Histone deacetylase 11

Protein Family

Histone deacetylase

UniProt Gene Name

HDAC11

UniProt Synonym Gene Names

HD11

UniProt Entry Name

HDA11_HUMAN

NCBI Protein Information

histone deacetylase 11

NCBI Summary for HDAC11

This gene encodes a class IV histone deacetylase. The encoded protein is localized to the nucleus and may be involved in regulating the expression of interleukin 10. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Apr 2009]

UniProt Comments for HDAC11

HDAC11: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Belongs to the histone deacetylase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Deacetylase; EC 3.5.1.98

Chromosomal Location of Human Ortholog: 3p25.1

Cellular Component: histone deacetylase complex; plasma membrane; nucleus

Molecular Function: NAD-dependent histone deacetylase activity (H3-K9 specific); NAD-dependent histone deacetylase activity (H3-K14 specific); NAD-dependent histone deacetylase activity (H4-K16 specific); histone deacetylase activity; transcription factor binding

Biological Process: transcription, DNA-dependent; regulation of transcription, DNA-dependent; histone deacetylation; chromatin modification; oligodendrocyte development

Research Articles on HDAC11

1. High HDAC11 expression is associated with neoplasms.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.