Rabbit Anti-BAFF-R Polyclonal Antibody – Cat# MBS840860

BAFF-R Antibody – Rabbit Polyclonal

Name: BAFF-R Antibody; Polyclonal; Rabbit; Human/Mouse/Rat-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS840860
Price: 215 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS840860

Background: Members in the TNF superfamily regulate immune responses and induce apoptosis. A novel member in the TNF family was recently identified by several groups and designated BAFF, BLyS, TALL-1, THANK, and zTNF4. BAFF/BLyS was characterized as a B cell… More details

DISCONTINUED
Click here to view our similar product(s) OR click here to contact our technical support team for suitable replacement.

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

BAFF-R, Polyclonal Antibody

Full Product Name

BAFF-R Antibody

Product Gene Name

anti-BAFF-R antibody

Product Synonym Names

TNFRSF13C; CD268; BAFF-R; MGC138235

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Form/Format

100 ug (0.5 mg/ml) affinity purified rabbit anti-BAFF-R polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal
Appearance: Colorless liquid

Purity/Purification

Affinity purified

Concentration

0.5 mg/ml (lot specific)

Preparation and Storage

At -20 degree C
Shelf Life: 12 months

Molecular Weight

17,576 Da

3D Structure

ModBase 3D Structure for Q9D8D0

Immunogen

Synthetic peptide surrounding amino acid 159 of mouse BAFF-R

Handling

The antibody solution should be gently mixed before use.

Applications Tested/Suitable for anti-BAFF-R antibody

Western Blot (WB)

Application Notes for anti-BAFF-R antibody

Western blotting (0.5-4 ug/ml). However, the optimal concentrations should be determined individually.

Other Notes

Small volumes of anti-BAFF-R antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for BAFF-R purchase

MBS840860 is an antibody targeting BAFF-R. Also known as BAFF-R Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for BAFF-R. It may not necessarily be applicable to this product.

NCBI GI #

16306481

NCBI GeneID

72049

NCBI Accession #

NP_082351.1

UniProt Primary Accession #

Q9D8D0

UniProt Related Accession #

Q9D8D0

GenBank Nucleotide #

NM_028075.2

NCBI Official Full Name

tumor necrosis factor receptor superfamily member 13C

NCBI Official Synonym Full Names

tumor necrosis factor receptor superfamily, member 13c

NCBI Official Symbol

Tnfrsf13c

NCBI Official Synonym Symbols

Bcmd; Baffr; Bcmd1; BAFF-R; Bcmd-1; Lvis22; 2010006P15Rik

UniProt Protein Name

Tumor necrosis factor receptor superfamily member 13C

UniProt Synonym Protein Names

B-cell maturation defect; B-cell-activating factor receptor; BAFF receptor; BAFF-R; BLyS receptor 3; CD_antigen: CD268

Protein Family

Tumor necrosis factor receptor superfamily

UniProt Gene Name

Tnfrsf13c

UniProt Synonym Gene Names

Baffr; Bcmd; Br3; BAFF-R

UniProt Entry Name

TR13C_MOUSE

NCBI Protein Information

tumor necrosis factor receptor superfamily member 13C

UniProt Comments for BAFF-R

BAFF-R: B-cell receptor specific for TNFSF13B/TALL1/BAFF/BLyS. Promotes the survival of mature B-cells and the B-cell response. Defects in TNFRSF13C are the cause of immunodeficiency common variable type 4 (CVID4); also called antibody deficiency due to BAFFR defect. CVID4 is a primary immunodeficiency characterized by antibody deficiency, hypogammaglobulinemia, recurrent bacterial infections and an inability to mount an antibody response to antigen. The defect results from a failure of B-cell differentiation and impaired secretion of immunoglobulins; the numbers of circulating B-cells is usually in the normal range, but can be low. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell surface; Membrane protein, integral; Receptor, misc.; Cell cycle regulation

Cellular Component: membrane; integral to membrane; external side of plasma membrane

Biological Process: B cell costimulation; regulation of immune response; B cell homeostasis; immune system process; T cell costimulation; positive regulation of B cell proliferation; positive regulation of germinal center formation; positive regulation of T cell proliferation; positive regulation of interferon-gamma biosynthetic process

Research Articles on BAFF-R

1. Syk-deficient B cells require BAFF receptor and CD19/PI3K signaling for their long-term survival.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.