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FGF-20 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS840882

Background: Fibroblast Growth Factor-20 (FGF-20) is a secreted heparin binding growth factor belonging to the FGF family. FGF-20 signals thromugh the FGFR 2c and 3c and is expressed during limb and brian development. Human FGF-20 is a 23.2 kDa protein… More details

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Sample Manual Insert View PDF
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Product Name
FGF-20, Polyclonal Antibody
Full Product Name
FGF-20 Antibody
Product Gene Name
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
200 ug (0.5 mg/ml) affinity purified rabbit anti- human FGF-20 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol and 0.01% thimerosal.
Appearance: Colorless liquid
Purity/Purification
Affinity purified
Concentration
0.5 mg/ml (lot specific)
Preparation and Storage
At -20 degree C
Shelf Life: 12 months
Molecular Weight
23,499 Da
OMIM
605558
3D Structure
ModBase 3D Structure for Q9NP95
Immunogen
E. coli expressed recombinant human FGF-20
Handling
The antibody solution should be gently mixed before use.
Applications Tested/Suitable for anti-FGF-20 antibody
Western Blot (WB)
Application Notes for anti-FGF-20 antibody
Western blot analysis (0.5-4 ug/ml). Recombinant human FGF-20 can be used as a positive control. However, the optimal conditions should be determined individually. Other applications have not been determined.

Testing Data of anti-FGF-20 antibody

Rabbit Anti-FGF-20 Polyclonal Antibody – Cat# MBS840882

Other Notes

Small volumes of anti-FGF-20 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for FGF-20 purchase

MBS840882 is an antibody targeting FGF-20. Also known as FGF-20 Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for FGF-20. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
fibroblast growth factor 20
NCBI Official Synonym Full Names
fibroblast growth factor 20
NCBI Official Symbol
FGF20
NCBI Official Synonym Symbols
RHDA2; FGF-20
UniProt Protein Name
Fibroblast growth factor 20
UniProt Gene Name
FGF20
UniProt Synonym Gene Names
FGF-20
UniProt Entry Name
FGF20_HUMAN
NCBI Protein Information
fibroblast growth factor 20

NCBI Summary for FGF-20

The protein encoded by this gene is a member of the fibroblast growth factor family. The fibroblast growth factors possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene product is a secreted neurotrophic factor but lacks a typical signal peptide. It is expressed in normal brain, particularly the cerebellum, and may regulate central nervous system development and function. Homodimerization of this protein was shown to regulate its receptor binding activity and concentration gradient in the extracellular matrix. Genetic variations of this gene have been associated with Parkinson disease susceptibility. [provided by RefSeq, Oct 2009]
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UniProt Comments for FGF-20

FGF20: Neurotrophic factor that regulates central nervous development and function. Belongs to the heparin-binding growth factors family.

Protein type: Cytokine

Chromosomal Location of Human Ortholog: 8p22

Cellular Component: extracellular region

Molecular Function: growth factor activity; fibroblast growth factor receptor binding

Biological Process: epidermal growth factor receptor signaling pathway; fibroblast growth factor receptor signaling pathway; phosphoinositide-mediated signaling; cell-cell signaling; inner ear receptor cell differentiation; nerve growth factor receptor signaling pathway; positive regulation of cell proliferation; insulin receptor signaling pathway; innate immune response; regulation of cardiac muscle cell proliferation; signal transduction

Disease: Renal Hypodysplasia/aplasia 2
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
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