Rabbit Anti-WNT-2 Polyclonal Antibody – Cat# MBS840919

WNT-2 Antibody – Rabbit Polyclonal

Name: WNT-2 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS840919
Price: 215 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS840919

Polyclonal Antibody to detect Wnt-2 in human samplesBackground: This protein belongs to the Wnt family of proteins. The WNT gene family consists of structurally related genes that encode secreted signaling proteins involved in the Wnt signaling pathway. Wnt… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

Wnt-2, Polyclonal Antibody

Full Product Name

Wnt-2 Antibody

Product Gene Name

anti-Wnt-2 antibody

Product Synonym Names

INT1L1; IRP; Int-1-like protein 1; Int-1-related protein

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

100 ug (0.5 mg/ml) of antibody in PBS pH 7.2 containing 0.01 % BSA, 0.01 % thimerosal, and 50 % glycerol.
Appearance: Colorless liquid

Purity/Purification

Affinity Purified Antibody

Concentration

0.5 mg/ml (lot specific)

Preparation and Storage

At -20 degree C
Shelf Life: 12 months

Molecular Weight

40,418 Da

OMIM

147870

3D Structure

ModBase 3D Structure for P09544

Immunogen

Recombinant human Wnt-2 protein

Positive Control

Western Blot: Recombinant protein

Handling

The antibody solution should be gently mixed before use.

Product Categories/Family for anti-Wnt-2 antibody

Antibodies & Supporting Tools; Primary Antibodies (A-Z)

Applications Tested/Suitable for anti-Wnt-2 antibody

Western Blot (WB)

Application Notes for anti-Wnt-2 antibody

Western blot: 1-4 ug/ml.

Other Notes

Small volumes of anti-Wnt-2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Wnt-2 purchase

MBS840919 is an antibody targeting Wnt-2. Also known as Wnt-2 Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for Wnt-2. It may not necessarily be applicable to this product.

NCBI GI #

4507927

NCBI GeneID

7472

NCBI Accession #

NP_003382.1

UniProt Primary Accession #

P09544

UniProt Secondary Accession #

Q75N05; Q9UDP9; A4D0V1

UniProt Related Accession #

P09544

GenBank Nucleotide #

NM_003391.2

NCBI Official Full Name

protein Wnt-2

NCBI Official Synonym Full Names

wingless-type MMTV integration site family member 2

NCBI Official Symbol

WNT2

NCBI Official Synonym Symbols

IRP; INT1L1

UniProt Protein Name

Protein Wnt-2

UniProt Synonym Protein Names

Int-1-like protein 1; Int-1-related protein; IRP

Protein Family

Protein

UniProt Gene Name

WNT2

UniProt Synonym Gene Names

INT1L1; IRP; IRP

UniProt Entry Name

WNT2_HUMAN

NCBI Protein Information

protein Wnt-2

NCBI Summary for Wnt-2

This gene is a member of the WNT gene family. The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. Alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Jul 2008]

UniProt Comments for Wnt-2

WNT2: Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters. Belongs to the Wnt family.

Protein type: Cell adhesion; Secreted, signal peptide; Extracellular matrix; Secreted; Cell development/differentiation

Chromosomal Location of Human Ortholog: 7q31.2

Cellular Component: extracellular matrix; proteinaceous extracellular matrix; extracellular space; cytoplasm; plasma membrane; extracellular region

Molecular Function: protein binding; frizzled binding; cytokine activity; receptor agonist activity

Biological Process: lens development in camera-type eye; Wnt receptor signaling pathway; cell fate commitment; atrial cardiac muscle morphogenesis; Wnt receptor signaling pathway through beta-catenin; neuron differentiation; positive regulation of fibroblast proliferation; cell-cell signaling; positive regulation of cell proliferation; positive regulation of mesenchymal cell proliferation; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription factor activity; positive regulation of endothelial cell proliferation; positive regulation of cardiac muscle cell proliferation; lung development

Research Articles on Wnt-2

1. Hypermethylation of WNT2 is associated with colorectal cancer.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.