Rabbit Anti-PDP2 Polyclonal Antibody – Cat# MBS840966

Pyruvate Dehydrogenase Phosphatase 2 (PDP2) Antibody – Rabbit Polyclonal

Name: PDP2 Antibody; Polyclonal; Rabbit; Human/Mouse/Rat-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS840966
Price: 215 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS840966

Background: PDP2, Pyruvate dehydrogenase phosphatase 2, catalyzes the dephosphorylation and activation of E1 component to reverse the effects of pyruvate dehydrogenase kinases. Pyruvate dehydrogenase (E1) is one of the three components (E1, E2, and E3) of the… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

Pyruvate Dehydrogenase Phosphatase 2 (PDP2), Polyclonal Antibody

Full Product Name

Pyruvate Dehydrogenase Phosphatase 2 (PDP2) Antibody

Product Gene Name

anti-PDP2 antibody

Product Synonym Names

pyruvate dehydrogenase (lipoamide) E1 component; beta subunit precursor; pyruvate decarboxylase.; pyruvate dehydrogenase; Pyruvic dehydrogenase; Sphingobacterium spiritivorum 33861

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Form/Format

200 ug (0.5 mg/ml) affinity purified rabbit anti-PDPC polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal
Appearance: Colorless liquid

Purity/Purification

Affinity purified

Concentration

0.5 mg/ml (lot specific)

Preparation and Storage

At -20 degree C
Shelf Life: 12 months

Molecular Weight

59,978 Da

OMIM

615499

Immunogen

Synthetic peptide surrounding amino acid 427 of human PDPC subunit 1.

Positive Control

Jurkat cell lysate, 3T3 cell lysate

Handling

The antibody solution should be gently mixed before use.

Applications Tested/Suitable for anti-PDP2 antibody

Western Blot (WB)

Application Notes for anti-PDP2 antibody

Western blot analysis (1-4 ug/ml). However, the optimal conditions should be determined individually. Jurkat or 3T3 cell lysate can be used as a positive control.

Other Notes

Small volumes of anti-PDP2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PDP2 purchase

MBS840966 is an antibody targeting PDP2. Also known as Pyruvate Dehydrogenase Phosphatase 2 (PDP2) Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for PDP2. It may not necessarily be applicable to this product.

NCBI GI #

41349497

NCBI GeneID

57546

NCBI Accession #

NP_065837.1

UniProt Secondary Accession #

A8K924

UniProt Related Accession #

Q9P2J9

GenBank Nucleotide #

NM_020786.2

NCBI Official Full Name

[Pyruvate dehydrogenase

NCBI Official Synonym Full Names

pyruvate dehyrogenase phosphatase catalytic subunit 2

NCBI Official Symbol

PDP2

NCBI Official Synonym Symbols

PPM2C2

UniProt Protein Name

[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial

UniProt Synonym Protein Names

Pyruvate dehydrogenase phosphatase catalytic subunit 2; PDPC 2

Protein Family

PWWP domain-containing protein

UniProt Gene Name

PDP2

UniProt Synonym Gene Names

KIAA1348; PDP 2; PDPC 2

UniProt Entry Name

PDP2_HUMAN

NCBI Protein Information

[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial

UniProt Comments for PDP2

PDP2: a protein phosphoserine phosphatase associated with the mitochondrial matrix that activates phosphorylated pyruvate dehydrogenase complex by dephosphorylation. The PDPs play crucial roles in switching metabolic flux from glycolysis towards oxidative phosphorylation. Catalyzes the dephosphorylation and concomitant reactivation of the alpha subunit of the E1 component of the pyruvate dehydrogenase complex . PDP2 consists of only a catalytic subunit. Belongs to the PP2C family.

Protein type: EC 3.1.3.43; Protein phosphatase, Ser/Thr (non-receptor); Mitochondrial

Chromosomal Location of Human Ortholog: 16q22.1

Cellular Component: mitochondrial matrix

Molecular Function: [pyruvate dehydrogenase (lipoamide)] phosphatase activity; metal ion binding; magnesium-dependent protein serine/threonine phosphatase activity

Biological Process: cellular metabolic process; regulation of acetyl-CoA biosynthetic process from pyruvate; pyruvate metabolic process

Research Articles on PDP2

1. Observational study of gene-disease association. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.