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LASS5 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS841098

Background: Lass5 also known as longevity assurance homolog 5 is a dihydroceramide synthase. It uses palrnitoyl-CoA as acyl donor and is involved in the synthesis of C14, C16 and C18-ceramide. More details

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Testing Data View PDF
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Product Overview

Product Name
LASS5, Polyclonal Antibody
Full Product Name
LASS5 Antibody
Product Gene Name
Product Synonym Names
CerS5; FLJ25304; LASS5; MGC45411; Trh4
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
100 ug (0.5 mg/ml) affinity purified rabbit anti-Lass5 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.
Appearance: Colorless liquid
Purity/Purification
Affinity purified
Concentration
0.5 mg/ml (lot specific)
Preparation and Storage
At -20 degree C
Shelf Life: 12 months
Molecular Weight
39,259 Da
OMIM
615335
Immunogen
Synthetic peptide surrounding amino acid 186 of human Lass5
Handling
The antibody solution should be gently mixed before use.
Applications Tested/Suitable for anti-LASS5 antibody
Western Blot (WB)
Application Notes for anti-LASS5 antibody
Western blotting (0.5-4 ug/ml). Multiple isoforms of Lass5 can be determined. Other applications have not been determined.

Testing Data of anti-LASS5 antibody

Rabbit Anti-LASS5 Polyclonal Antibody – Cat# MBS841098

Other Notes

Small volumes of anti-LASS5 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for LASS5 purchase

MBS841098 is an antibody targeting LASS5. Also known as LASS5 Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for LASS5. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
LASS5 protein
NCBI Official Synonym Full Names
ceramide synthase 5
NCBI Official Symbol
CERS5
NCBI Official Synonym Symbols
Trh4; LASS5
UniProt Protein Name
Ceramide synthase 5
UniProt Synonym Protein Names
LAG1 longevity assurance homolog 5
UniProt Gene Name
CERS5
UniProt Synonym Gene Names
LASS5; CerS5
UniProt Entry Name
CERS5_HUMAN
NCBI Protein Information
ceramide synthase 5

NCBI Summary for LASS5

This gene encodes a protein that belongs to the TLC (TRAM, LAG1 and CLN8 homology domains) family of proteins. The encoded protein functions in the synthesis of ceramide, a lipid molecule that is involved in a several cellular signaling pathways. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
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UniProt Comments for LASS5

LASS5: May be either a bona fide (dihydro)ceramide synthase or a modulator of its activity. When overexpressed in cells is involved in the production of sphingolipids containing mainly one fatty acid donor (N-linked palmitoyl- (C16) ceramide) in a fumonisin B1-independent manner.

Protein type: DNA-binding; Membrane protein, integral; EC 2.3.1.24; Transferase; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 12q13.12

Cellular Component: endoplasmic reticulum membrane; nuclear membrane; endoplasmic reticulum; integral to membrane

Molecular Function: DNA binding; sphingosine N-acyltransferase activity

Biological Process: sphingolipid metabolic process; sphingolipid biosynthetic process; ceramide biosynthetic process
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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