Rabbit Anti-SPTAN1 Polyclonal Antibody – Cat# MBS841239

Alpha-Fodrin (SPTAN1) Antibody – Rabbit Polyclonal

Name: SPTAN1 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS841239
Price: 215 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS841239

Background: Fodrin is a universally expressed membrane-associated cytoskeletal protein consisting of alpha- and beta-subunits. The protein is important for maintaining normal membrane structure and supporting cell surface protein function. alpha-Fodrin is one… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

alpha-Fodrin (Sptan1), Polyclonal Antibody

Full Product Name

alpha-Fodrin Antibody

Product Gene Name

anti-Sptan1 antibody

Product Synonym Names

SPTAN1; FLJ44613; SPTA2

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

100 ug (0.5 mg/ml) affinity purified rabbit anti-alpha-Fodrin polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.
Appearance: Colorless liquid

Purity/Purification

Affinity purified

Concentration

0.5 mg/ml (lot specific)

Preparation and Storage

At -20 degree C
Shelf Life: 12 months

Molecular Weight

282,340 Da

3D Structure

ModBase 3D Structure for P16546

Immunogen

Synthetic peptide surrounding amino acid 162 of mouse alpha-Fodrin

Handling

The antibody solution should be gently mixed before use.

Applications Tested/Suitable for anti-Sptan1 antibody

Western Blot (WB), Immunohistochemistry (IHC)

Application Notes for anti-Sptan1 antibody

Western blot analysis (0.5-4 ug/ml) and in in Immunohistochemistry (10-20 ug/ml).

Other Notes

Small volumes of anti-Sptan1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Sptan1 purchase

MBS841239 is an antibody targeting Sptan1. Also known as alpha-Fodrin Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for Sptan1. It may not necessarily be applicable to this product.

NCBI GI #

122066202

NCBI GeneID

20740

NCBI Accession #

P16546.4

UniProt Primary Accession #

P16546

UniProt Secondary Accession #

Q8K380; Q9CT05; A3KGU6; A3KGU8

UniProt Related Accession #

P16546

NCBI Official Full Name

Spectrin alpha chain, non-erythrocytic 1

NCBI Official Synonym Full Names

spectrin alpha, non-erythrocytic 1

NCBI Official Symbol

Sptan1

NCBI Official Synonym Symbols

Spna2; Spna-2; 2610027H02Rik

UniProt Protein Name

Spectrin alpha chain, non-erythrocytic 1

UniProt Synonym Protein Names

Alpha-II spectrin; Fodrin alpha chain

Protein Family

Spectrin

UniProt Gene Name

Sptan1

UniProt Synonym Gene Names

Spna2; Spta2

UniProt Entry Name

SPTN1_MOUSE

NCBI Protein Information

spectrin alpha chain, non-erythrocytic 1

UniProt Comments for Sptan1

SPTAN1: a cytoskeletal protein which seems to be involved in secretion, interacts with calmodulin in a calcium-dependent manner and is thus candidate for the calcium-dependent movement of the cytoskeleton at the membrane. Capable to forming dimers which can further associate to tetramers.

Protein type: Cytoskeletal; Adaptor/scaffold; Motility/polarity/chemotaxis

Cellular Component: cortical cytoskeleton; protein complex; intracellular membrane-bound organelle; paranode region of axon; fascia adherens; Z disc; microtubule cytoskeleton; cytoskeleton; membrane; cytoplasm; plasma membrane; myelin sheath; lateral plasma membrane; vesicle

Molecular Function: calmodulin binding; protein binding; syntaxin binding; spectrin binding; protein heterodimerization activity; metal ion binding; protein complex binding; protein N-terminus binding; calcium ion binding; actin binding

Biological Process: actin filament capping; actin cytoskeleton reorganization

Research Articles on Sptan1

1. Fodrin is a regulatory transporter of gamma-tubulin to the centrosomes for normal progression of mitosis.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-Sptan1 antibody

Reference Product	PubMed Publications
Casp3 antibody	>2 publications with Sptan1 and Casp3

Pathways associated with anti-Sptan1 antibody

Products by Pathway	Pathway Diagram
ARMS-mediated Activation Pathway antibodies	ARMS-mediated Activation Pathway Diagram
Apoptosis Pathway antibodies	Apoptosis Pathway Diagram
Apoptotic Cleavage Of Cellular Proteins Pathway antibodies	Apoptotic Cleavage Of Cellular Proteins Pathway Diagram
Apoptotic Execution Phase Pathway antibodies	Apoptotic Execution Phase Pathway Diagram
Axon Guidance Pathway antibodies	Axon Guidance Pathway Diagram
Caspase-mediated Cleavage Of Cytoskeletal Proteins Pathway antibodies	Caspase-mediated Cleavage Of Cytoskeletal Proteins Pathway Diagram
Cell-Cell Communication Pathway antibodies	Cell-Cell Communication Pathway Diagram
Cytokine Signaling In Immune System Pathway antibodies	Cytokine Signaling In Immune System Pathway Diagram
DAP12 Interactions Pathway antibodies	DAP12 Interactions Pathway Diagram
DAP12 Signaling Pathway antibodies	DAP12 Signaling Pathway Diagram

Organs/Tissues associated with anti-Sptan1 antibody

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>7 publications with Sptan1 and Brain
Blood Antibodies	>4 publications with Sptan1 and Blood
Stomach Antibodies	>1 publications with Sptan1 and Stomach
Heart Antibodies	>1 publications with Sptan1 and Heart
Skin Antibodies	>1 publications with Sptan1 and Skin
Lung Antibodies	>1 publications with Sptan1 and Lung
Intestine Antibodies	>1 publications with Sptan1 and Intestine
Muscle Antibodies	>1 publications with Sptan1 and Muscle
Eye Antibodies	>1 publications with Sptan1 and Eye