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Tubastatin A

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS841914

Background: Cell-permeable. A potent and selective HDAC6 (histone deacetylase 6) inhibitor. Displays 1093-fold selectivity over HDAC1 (IC?? values of 15 nM for HDAC6 vs 16.4 uM for HDAC1). Tubastatin A was substantially more selective than the known HDAC6… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
Tubastatin A, Biochemical
Full Product Name
Tubastatin A
Product Synonym Names
n-Hydroxy-4-((2-methyl-3,4-dihydro-1H-pyrido[4,3-b]-indol-5(2H)-yl)methyl)benzamide
Form/Format
Appearance: Off-white solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
At -20 degree C
Shelf Life: 24 months
Molecular Weight
371.86
CAS Number
1239262-52-2
Structure Available?
Yes
Salt Form
No
Cell-Permeable?
Yes
MDL Number
MFCD18071463
PubChem CID
57336514
Solubility/Reconstitution Instructions
DMSO (~90 mg/ml) or Water (~ 4mg/ml) or 2% TWEEN-80/water (~2 mg/ml) or 30% PEG (avg. MW = 400 g/mol)/50 mM phosphate buffer (pH = 2.25) (25 mg/ml) (heating is required to initially dissolve the compound).
SMILES
CN1CCC2=C(C1)C3=CC=CC=C3N2CC4=CC=C(C=C4)C(=O)NO.Cl
InChi
InChI=1S/C20H21N3O2.ClH/c1-22-11-10-19-17(13-22)16-4-2-3-5-18(16)23(19)12-14-6-8-15(9-7-14)20(24)21-25;/h2-9,25H,10-13H2,1H3,(H,21,24);1H
InChi Key
LJTSJTWIMOGKRJ-UHFFFAOYSA-N
Handling
Protect from air and light

Product Categories/Family for Tubastatin A biochemical

Biochemicals; Enzyme Inhibitors; HDAC Inhibitors; Biochemicals; Biochemicals (A-Z)

Structure of Tubastatin A biochemical

Tubastatin A Biochemical – Cat# MBS841914

Other Notes

Small volumes of Tubastatin A biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Tubastatin A purchase

MBS841914 is a biochemical targeting Tubastatin A.
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