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PX 12

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS841915

Background: PX-12 is an irreversible inhibitor of thioredoxin-1 (TRX-1) (Ki = 31 uM). It decreases the expression of HIF-1alpha, VEGF and iNOS (IC?? values are 7.2, ~10 and 18.1 muM respectively). Also known to display antitumor activity and inhibits tubulin… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
PX 12, Biochemical
Full Product Name
PX 12
Product Gene Name
PX 12 biochemical
Product Synonym Names
2-[(1-Methylpropyl)dithio]-1H-imidazole; IV-2
Form/Format
Appearance: Beige solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
At -20 degree C
Shelf Life: 24 months
Molecular Weight
188.31
CAS Number
141400-58-0
Structure Available?
Yes
Salt Form
No
Cell-Permeable?
Yes
MDL Number
MFCD18086851
PubChem CID
219104
Solubility/Reconstitution Instructions
DMSO (100 mM)
SMILES
CCC(C)SSC1=NC=CN1
InChi
InChI=1S/C7H12N2S2/c1-3-6(2)10-11-7-8-4-5-9-7/h4-6H,3H2,1-2H3,(H,8,9)
InChi Key
BPBPYQWMFCTCNG-UHFFFAOYSA-N
Handling
Protect from light and moisture

Product Categories/Family for PX 12 biochemical

Enzyme Inhibitors; Thioredoxin inhibitors and Biochemicals; Enzyme Inhibitors; Thioredoxin inhibitors and Biochemicals (A-Z)

Structure of PX 12 biochemical

PX 12 Biochemical – Cat# MBS841915

Other Notes

Small volumes of PX 12 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PX 12 purchase

MBS841915 is a biochemical targeting PX 12.
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