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BIX01289

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS841930

Background: BIX01289 is a potent MEK5 inhibitor (IC?? = 1.5 nM). Also inhibits ERK5 catalytic activity (IC?? = 59 nM). Does not inhibit closely related kinases MEK1, MEK2, ERK2 and JNK2. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
BIX01289, Biochemical
Full Product Name
BIX01289
Product Gene Name
BIX01289 biochemical
Product Synonym Names
(Z)-3-(((3-((dimethylamino)methyl)phenyl)amino)(phenyl)methylene)-N,N-dimethyl-2-oxoindoline-6-carboxamide
Form/Format
Appearance: Crystalline solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
At -20 degree C
Shelf Life: 36 months
Molecular Weight
440.54
CAS Number
1094614-85-3
Structure Available?
Yes
Salt Form
No
Cell-Permeable?
Yes
PubChem CID
46931012
Solubility/Reconstitution Instructions
DMSO (>50 mg/ml)
SMILES
CN(C)CC1=CC(=CC=C1)NC(=C2C3=C(C=C(C=C3)C(=O)N(C)C)NC2=O)C4=CC=CC=C4
InChi
InChI=1S/C27H28N4O2/c1-30(2)17-18-9-8-12-21(15-18)28-25(19-10-6-5-7-11-19)24-22-14-13-20(27(33)31(3)4)16-23(22)29-26(24)32/h5-16,28H,17H2,1-4H3,(H,29,32)/b25-24-
InChi Key
HOMJAAIVTDVQJA-IZHYLOQSSA-N
Handling
Protect from air and light

Product Categories/Family for BIX01289 biochemical

Enzyme Inhibitors; Protein Kinase Inhibitors; MAP Kinase/MEK InhibitorsBiochemicals; Enzyme Inhibitors; Protein Kinase Inhibitors; MAP Kinase/MEK InhibitorsSignaling Pathways; MAP Kinase Pathway; MAP Kinase/MEK InhibitorsBiochemicals; Biochemicals (A-Z)

Structure of BIX01289 biochemical

BIX01289 Biochemical – Cat# MBS841930

Other Notes

Small volumes of BIX01289 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for BIX01289 purchase

MBS841930 is a biochemical targeting BIX01289.
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