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AKR1C3 Inhibitor I

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS841936

Background: A highly potent and selective inhibitor of the type 5 17-beta-hydroxysteroid dehydrogenase AKR1C3. In repeat assays it showed an IC?? of 0.013 +/- 0.003 muM for AKR1C3, compared with 20.3 +/- 3.8 muM against AKR1C1 and >30 muM against AKR1C2 and… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
AKR1C3 Inhibitor I, Biochemical
Full Product Name
AKR1C3 Inhibitor I
Product Synonym Names
3-(3,4-Dihydroisoquinolin2(1H)-ylsulfonyl)benzoic acid
Form/Format
Appearance: White solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
At -20 degree C
Shelf Life: 36 months
Molecular Weight
317.36
Structure Available?
Yes
Salt Form
No
Cell-Permeable?
Yes
Solubility/Reconstitution Instructions
DMSO
SMILES
O=S(C1=CC(C(O)=O)=CC=C1)(N2CCC(C=CC=C3)=C3C2)=O
InChi
InChI=1S/C16H15NO4S/c18-16(19)13-6-3-7-15(10-13)22(20,21)17-9-8-12-4-1-2-5-14(12)11-17/h1-7,10H,8-9,11H2,(H,18,19)
InChi Key
ZGVIUMKHTXKKOX-UHFFFAOYSA-N
Handling
Protect from air and light

Other Notes

Small volumes of AKR1C3 Inhibitor I biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for AKR1C3 Inhibitor I purchase

MBS841936 is a biochemical targeting AKR1C3 Inhibitor I.
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