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Torin 2

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS841938

Background: A potent, selective and ATP-competitive mTOR inhibitor (IC?? = 2.1 nM for mTORC1). Torin 2 displays 800-fold selectivity for mTOR over PI3K (cellular EC?? values of 0.25 nM and 200 nM, respectively) and exhibits 100-fold binding selectivity… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
Torin 2, Biochemical
Full Product Name
Torin 2
Product Synonym Names
9-(6-Amino-3-pyridinyl)-1-[3-(trifl-uoromethyl)phenyl]-benzo[h]-1,6-naphthyridin-2(1H)--one
Form/Format
Appearance: Yellow solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
At -20 degree C
Shelf Life: 24 months
Molecular Weight
432.4
CAS Number
1223001-51-1
Structure Available?
Yes
Salt Form
No
Cell-Permeable?
Yes
MDL Number
MFCD18782652
PubChem CID
51358113
Solubility/Reconstitution Instructions
DMSO (~8 mg/ml)
SMILES
C1=CC(=CC(=C1)N2C(=O)C=CC3=CN=C4C=CC(=CC4=C32)C5=CN=C(C=C5)N)C(F)(F)F
InChi
InChI=1S/C24H15F3N4O/c25-24(26,27)17-2-1-3-18(11-17)31-22(32)9-6-16-13-29-20-7-4-14(10-19(20)23(16)31)15-5-8-21(28)30-12-15/h1-13H,(H2,28,30)
InChi Key
GUXXEUUYCAYESJ-UHFFFAOYSA-N
Handling
Protect from air and moisture

Structure of Torin 2 biochemical

Torin 2 Biochemical – Cat# MBS841938

Other Notes

Small volumes of Torin 2 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Torin 2 purchase

MBS841938 is a biochemical targeting Torin 2.
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