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SANT-1

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS841955

Background: Cell-permeable. A potent inhibitor of Sonic hedgehog (Shh) signaling; high affinity antagonist of smoothened activity (Kd = 1.2 nM). Inhibits smoothened agonist effects with an IC??of 20 nM in Shh-LIGHT2 cells. SANT-1 inhibits both wild type and… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
SANT-1, Biochemical
Full Product Name
SANT-1
Product Gene Name
SANT-1 biochemical
Product Synonym Names
N-[(3,5-dimethyl-1-phenyl-1H-pyrazol-4-yl)methylene]-4- (phenylmethyl)-1-piperazinamine
Form/Format
Appearance: Pale yellow solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
At -20 degree C
Shelf Life: 60 months
Molecular Weight
373.49
CAS Number
304909-07-7
Structure Available?
Yes
Salt Form
No
Cell-Permeable?
Yes
MDL Number
MFCD01827306
PubChem CID
6878030
Solubility/Reconstitution Instructions
DMSO (~50 mM) or EtOH (~25 mM)
SMILES
CC1=C(C(=NN1C2=CC=CC=C2)C)C=NN3CCN(CC3)CC4=CC=CC=C4
InChi
InChI=1S/C23H27N5/c1-19-23(20(2)28(25-19)22-11-7-4-8-12-22)17-24-27-15-13-26(14-16-27)18-21-9-5-3-6-10-21/h3-12,17H,13-16,18H2,1-2H3/b24-17+
InChi Key
FOORCIAZMIWALX-JJIBRWJFSA-N
Handling
Protect from light and air

Product Categories/Family for SANT-1 biochemical

Biochemicals; Enzyme Inhibitors; Hedgehog (Hh) Signaling Pathway Antagonists and Biochemicals (A-Z)

Structure of SANT-1 biochemical

SANT-1 Biochemical – Cat# MBS841955

Other Notes

Small volumes of SANT-1 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SANT-1 purchase

MBS841955 is a biochemical targeting SANT-1.
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