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AGI-5198

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS841959

Background: A potent, selective inhibitor of mutant IDH1 (isocitrate dehydrogenase 1). AGI-5198 inhibits IDH1 R132H and R132C mutants in vitro with IC?? values of 0.07 and 0.16 uM, respectively, but not wild-type IDH1, wild-type IDH2, or IDH2 mutants (IC?? s… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
AGI-5198, Biochemical
Full Product Name
AGI-5198
Product Gene Name
AGI-5198 biochemical
Product Synonym Names
N-[2-(cyclohexylamino)-1-(2-methylphenyl)-2-oxoethyl]-N-(3-fluorophenyl)-2-methyl-1H-imidazole-1-acetamide; IDH-C35
Form/Format
Appearance: Crystalline solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
At -20 degree C
Shelf Life: 36 months
Molecular Weight
462.56
CAS Number
1355326-35-0
Structure Available?
Yes
Salt Form
No
Cell-Permeable?
Yes
PubChem CID
56645356
Solubility/Reconstitution Instructions
DMSO (~25 mg/ml) or Ethanol (~ 15 mg/ml)
SMILES
CC1=CC=CC=C1C(C(=O)NC2CCCCC2)N(C3=CC(=CC=C3)F)C(=O)CN4C=CN=C4C
InChi
InChI=1S/C27H31FN4O2/c1-19-9-6-7-14-24(19)26(27(34)30-22-11-4-3-5-12-22)32(23-13-8-10-21(28)17-23)25(33)18-31-16-15-29-20(31)2/h6-10,13-17,22,26H,3-5,11-12,18H2,1-2H3,(H,30,34)
InChi Key
FNYGWXSATBUBER-UHFFFAOYSA-N
Handling
Protect from light and moisture

Product Categories/Family for AGI-5198 biochemical

Enzyme Inhibitors; Isocitrate Dehydrogenase (IDH) Inhibitors and Biochemicals; Enzyme Inhibitors; Isocitrate Dehydrogenase (IDH) Inhibitors and Biochemicals; Biochemicals (A-Z)

Structure of AGI-5198 biochemical

AGI-5198 Biochemical – Cat# MBS841959

Other Notes

Small volumes of AGI-5198 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for AGI-5198 purchase

MBS841959 is a biochemical targeting AGI-5198.
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