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MLN-4924

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS841960

Background: A potent and selective inhibitor of NEDD8 (Neural precursor cell expressed, developmentally down-regulated 8)-activating enzyme (NAE) (IC?? = 4.7 nM) with potential anticancer activity. NAE activates NEDD8, an ubiquitin-like (UBL) protein that… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
MLN-4924, Biochemical
Full Product Name
MLN-4924
Product Gene Name
MLN-4924 biochemical
Product Synonym Names
(1S,2S,4R)-4-(4-(((S)-2,3-dihydro-1H-inden-1-yl)amino)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-2-hydroxycyclopentylmethyl sulfamate
Form/Format
Appearance: White solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
At -20 degree C
Shelf Life: 24 months
Molecular Weight
443.53
CAS Number
905579-51-3
Structure Available?
Y
Salt Form
No
Cell-Permeable?
Yes
PubChem CID
16720766
Solubility/Reconstitution Instructions
DMSO (~10 mg/ml)
SMILES
C1CC2=CC=CC=C2C1NC3=NC=NC4=C3C=CN4C5CC(C(C5)O)COS(=O)(=O)N
InChi
InChI=1S/C21H25N5O4S/c22-31(28,29)30-11-14-9-15(10-19(14)27)26-8-7-17-20(23-12-24-21(17)26)25-18-6-5-13-3-1-2-4-16(13)18/h1-4,7-8,12,14-15,18-19,27H,5-6,9-11H2,(H2,22,28,29)(H,23,24,25)/t14-,15+,18-,19-/m0/s1
InChi Key
MPUQHZXIXSTTDU-QXGSTGNESA-N
Handling
Protect from air and light

Product Categories/Family for MLN-4924 biochemical

Enzyme Inhibitors; Ubiquitin Proteasome Pathway Inhibitors and Biochemicals; Enzyme Inhibitors; Ubiquitin Proteasome Pathway Inhibitors and Signaling Pathways; Ubiquitin Proteasome Pathway; Inhibitors and Biochemicals; Biochemicals (A-Z)

Structure of MLN-4924 biochemical

MLN-4924 Biochemical – Cat# MBS841960

Other Notes

Small volumes of MLN-4924 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MLN-4924 purchase

MBS841960 is a biochemical targeting MLN-4924.
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