• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

ABT-737

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS841979

Background: A small-molecule inhibitor of the anti-apoptotic proteins Bcl-2, Bcl-X(L) and Bcl-w. In vitro, ABT-737 binds Bcl-xL, Bcl-2 and Bcl-w with comparable high affinity, while it has over 1000-fold lower affinities for Bcl-B, Bfl-1 and Mcl-1. Displays… More details

DISCONTINUED
Click here to view our similar product(s) OR click here to contact our technical support team for suitable replacement.
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Product Name
ABT-737, Biochemical
Full Product Name
ABT-737
Product Gene Name
ABT-737 biochemical
Product Synonym Names
4-[4-[(4'-Chloro[1,1'-biphenyl]-2-yl)methyl]-1-piperazinyl]-N-[[4-[[(1R)-3-(dimethylamino)-1-[(phenylthio)methyl]propyl]amino]-3-nitrophenyl]sulfonyl]benzamide
Form/Format
Appearance: Crystalline solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
At -20 degree C
Shelf Life: 24 months
Molecular Weight
813.43
CAS Number
852808-04-9
Structure Available?
Yes
Salt Form
No
Cell-Permeable?
Yes
PubChem CID
11228183
Solubility/Reconstitution Instructions
DMSO (> 100 mg/ml)
SMILES
CN(C)CCC(CSC1=CC=CC=C1)NC2=C(C=C(C=C2)S(=O)(=O)NC(=O)C3=CC=C(C=C3)N4CCN(CC4)CC5=CC=CC=C5C6=CC=C(C=C6)Cl)[N+](=O)[O-]
InChi
InChI=1S/C42H45ClN6O5S2/c1-46(2)23-22-35(30-55-37-9-4-3-5-10-37)44-40-21-20-38(28-41(40)49(51)52)56(53,54)45-42(50)32-14-18-36(19-15-32)48-26-24-47(25-27-48)29-33-8-6-7-11-39(33)31-12-16-34(43)17-13-31/h3-21,28,35,44H,22-27,29-30H2,1-2H3,(H,45,50)/t35-/m1/s1
InChi Key
HPLNQCPCUACXLM-PGUFJCEWSA-N
Handling
Protect from air and light

Product Categories/Family for ABT-737 biochemical

Enzyme Inhibitors; Bcl-2 Inhibitors and Biochemicals; Enzyme Inhibitors; Bcl-2 Inhibitors and Biochemicals; Biochemicals (A-Z)

Structure of ABT-737 biochemical

ABT-737 Biochemical – Cat# MBS841979

Other Notes

Small volumes of ABT-737 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ABT-737 purchase

MBS841979 is a biochemical targeting ABT-737.
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000