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LDN-57444

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS841982

Background: Cell-permeable. LDN-57444 is a potent, reversible, competitive and active site-directed inhibitor of UCHL1 (Ki = 0.4 muM). Decreases proteasome activity and increases levels of ubiquitinated proteins. Induces apoptosis. Causes dramatic alterations… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
LDN-57444, Biochemical
Full Product Name
LDN-57444
Product Gene Name
LDN-57444 biochemical
Product Synonym Names
3-(O-acetyloxime); 5-chloro-1-[(2,5-dichlorophenyl)methyl]-1H-Indole-2,3-dione; C30; LDN 57444
Form/Format
Appearance: Yellow solid
Purity/Purification
>=98% by TLC
Preparation and Storage
At -20 degree C
Shelf Life: 24 months
Molecular Weight
397.64
CAS Number
668467-91-2
Structure Available?
Yes
Salt Form
No
Cell-Permeable?
Yes
MDL Number
MFCD09037562
PubChem CID
16760696
Solubility/Reconstitution Instructions
DMSO (20 mg/ml)
SMILES
CC(=O)ON=C1C2=C(C=CC(=C2)Cl)N(C1=O)CC3=C(C=CC(=C3)Cl)Cl
InChi
InChI=1S/C17H11Cl3N2O3/c1-9(23)25-21-16-13-7-12(19)3-5-15(13)22(17(16)24)8-10-6-11(18)2-4-14(10)20/h2-7H,8H2,1H3/b21-16-
InChi Key
OPQRFPHLZZPCCH-PGMHBOJBSA-N
Handling
Protect from air and light

Product Categories/Family for LDN-57444 biochemical

Biochemicals; Enzyme Inhibitors; DUBs (Deubiquitinating Enzymes) and related Inhibitors and Ubiquitin Proteasome Pathway Inhibitors and Biochemicals (A-Z)

Structure of LDN-57444 biochemical

LDN-57444 Biochemical – Cat# MBS841982

Other Notes

Small volumes of LDN-57444 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for LDN-57444 purchase

MBS841982 is a biochemical targeting LDN-57444.
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