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U0126

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS841983

Background: Potent and selective non-competitive inhibitor of MAP kinase kinase(MEK). Inhibits MEK-1 and MEK-2 (IC?? values of 0.07 and 0.06 uM respectively) with little or no effect on the activities of PKC, Abl, Raf, MEKK, ERK, JNK, MKK-3, MKK-4/SEK, MKK-6,… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
U0126, Biochemical
Full Product Name
U0126
Product Gene Name
U0126 biochemical
Product Synonym Names
1,4-Diamino-2,3-dicyano-1,4-bis(o-aminophenylmercapto)butadiene
Form/Format
Appearance: White to off-white solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
At -20 degree C
Shelf Life: 24 months
Molecular Weight
380.48
CAS Number
109511-58-2
Structure Available?
Yes
Salt Form
No
Cell-Permeable?
Yes
MDL Number
MFCD01861186
PubChem CID
3006531
Solubility/Reconstitution Instructions
DMSO (>10 mg/ml)
SMILES
C1=CC=C(C(=C1)N)SC(=C(C#N)C(=C(N)SC2=CC=CC=C2N)C#N)N
InChi
InChI=1S/C18H16N6S2/c19-9-11(17(23)25-15-7-3-1-5-13(15)21)12(10-20)18(24)26-16-8-4-2-6-14(16)22/h1-8H,21-24H2/b17-11+,18-12+
InChi Key
DVEXZJFMOKTQEZ-JYFOCSDGSA-N
Handling
Protect from air and light

Structure of U0126 biochemical

U0126 Biochemical – Cat# MBS841983

Other Notes

Small volumes of U0126 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for U0126 purchase

MBS841983 is a biochemical targeting U0126.
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