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KT5823

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS841993

Background: Cell-permeable. KT5823 is a derivative of K-252a that acts as a selective inhibitor of Protein kinase G (PKG) (Ki = 0.234 uM). Inhibits other kinases at much higher concentrations (Ki's for PKA = 4 muM and for MLCK=>10 muM). More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
KT5823, Biochemical
Full Product Name
KT5823
Product Gene Name
KT5823 biochemical
Product Synonym Names
2,3,9,10,11,12-hexahydro-10R-methoxy-2,9-dimethyl-1-oxo- 9S,12R-epoxy-1H-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4- i][1,]benzodiazocine-10-carboxylic acid, methyl ester
Form/Format
Appearance: White solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
At -20 degree C
Shelf Life: 24 months
Molecular Weight
495.53
CAS Number
126643-37-6
Structure Available?
Yes
Salt Form
No
Cell-Permeable?
Yes
MDL Number
MFCD09878278
PubChem CID
3843
Solubility/Reconstitution Instructions
DMSO (20 mg/ml)
SMILES
CC12C(CC(O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CN(C6=O)C)(C(=O)OC)OC
InChi
InChI=1S/C29H25N3O5/c1-28-29(36-4,27(34)35-3)13-20(37-28)31-18-11-7-5-9-15(18)22-23-17(14-30(2)26(23)33)21-16-10-6-8-12-19(16)32(28)25(21)24(22)31/h5-12,20H,13-14H2,1-4H3
InChi Key
QTYMDECKVKSGSM-UHFFFAOYSA-N
Handling
Protect from air and light

Product Categories/Family for KT5823 biochemical

Enzyme Inhibitors; Protein Kinase Inhibitors; Protein Kinase G (PKG) Inhibitors and Biochemicals; Enzyme Inhibitors; Protein Kinase Inhibitors; Protein Kinase G (PKG) Inhibitors and Biochemicals (A-Z)

Structure of KT5823 biochemical

KT5823 Biochemical – Cat# MBS841993

Other Notes

Small volumes of KT5823 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for KT5823 purchase

MBS841993 is a biochemical targeting KT5823.
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