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PD184352 (CI-1040)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS842044

Background: A highly potent ATP-noncompetitive MEK inhibitor. It inhibits MEK with an in vitro IC?? of 1-1.3 nM. It does not inhibit other kinases. Highly recommended tool to inhibit MKK1 or MKK1 plus MKK5. More details

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Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
PD184352, Biochemical
Full Product Name
PD184352
Product Gene Name
PD184352 biochemical
Product Synonym Names
CI-1040
Form/Format
Appearance: Crystalline solid
Purity/Purification
>=99% by HPLC
Preparation and Storage
At -20 degree C
Shelf Life: 24 months
Molecular Weight
478.67
CAS Number
212631-79-3
Structure Available?
Yes
Salt Form
No
Cell-Permeable?
Yes
MDL Number
MFCD02683961
PubChem CID
6918454
Solubility/Reconstitution Instructions
DMSO (600 mg/ml)
SMILES
C1CC1CONC(=O)C2=C(C(=C(C=C2)F)F)NC3=C(C=C(C=C3)I)Cl
InChi
InChI=1S/C17H14ClF2IN2O2/c18-12-7-10(21)3-6-14(12)22-16-11(4-5-13(19)15(16)20)17(24)23-25-8-9-1-2-9/h3-7,9,22H,1-2,8H2,(H,23,24)
InChi Key
GFMMXOIFOQCCGU-UHFFFAOYSA-N
Handling
Protect from light and moisture

Structure of PD184352 biochemical

PD184352 CI-1040 Biochemical – Cat# MBS842044

Other Notes

Small volumes of PD184352 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PD184352 purchase

MBS842044 is a biochemical targeting PD184352.
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