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Tariquidar

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS842077

Background: Tariquidar is a potent, specific, noncompetitive inhibitor of P-glycoprotein (P-gp) (Kd = 5.1 nM). Tariquidar inhibits the ATPase activity of P-gp, suggesting that the modulating effect is derived from the inhibition of substrate binding,… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
Tariquidar, Biochemical
Full Product Name
Tariquidar
Product Synonym Names
N-[2-[[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]carbamoyl]-4,5-dimethoxyphenyl]quinoline-3-carboxamide; XR9576; XR 9576; XR-9576,Tariquidar
Form/Format
Appearance: Light yellow solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
At -20 degree C
Shelf Life: 36 months
Molecular Weight
646.73
CAS Number
206873-63-4
Structure Available?
Yes
Salt Form
No
Cell-Permeable?
Yes
PubChem CID
148201
Solubility/Reconstitution Instructions
DMSO (>6 mg/ml)
SMILES
COC1=C(C=C2CN(CCC2=C1)CCC3=CC=C(C=C3)NC(=O)C4=CC(=C(C=C4NC(=O)C5=CC6=CC=CC=C6N=C5)OC)OC)OC
InChi
InChI=1S/C38H38N4O6/c1-45-33-18-25-14-16-42(23-28(25)19-34(33)46-2)15-13-24-9-11-29(12-10-24)40-38(44)30-20-35(47-3)36(48-4)21-32(30)41-37(43)27-17-26-7-5-6-8-31(26)39-22-27/h5-12,17-22H,13-16,23H2,1-4H3,(H,40,44)(H,41,43)
InChi Key
LGGHDPFKSSRQNS-UHFFFAOYSA-N
Handling
Protect from air and light

Other Notes

Small volumes of Tariquidar biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Tariquidar purchase

MBS842077 is a biochemical targeting Tariquidar.
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