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XL765

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS842087

Background: XL765 is a dual inhibitor of mTOR/PI3K with potential anticancer activities. XL765 inhibits both PI3 kinase and mTOR kinase, which may result in tumor cell apoptosis and growth inhibition in susceptible tumor cell populations. Activation of the… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
XL765, Biochemical
Full Product Name
XL765
Product Gene Name
XL765 biochemical
Product Synonym Names
2-Amino-8-ethyl-4-methyl-6-(lH-pyrazol-5-yl)pyrido[2,3-d]pyrimidin-7(8H)-one; SAR245409
Form/Format
Appearance: White solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
At -20 degree C
Shelf Life: 24 months
Molecular Weight
270.29
CAS Number
934493-76-2
Structure Available?
Y
Salt Form
No
Cell-Permeable?
Yes
PubChem CID
16123056
Solubility/Reconstitution Instructions
DMSO
SMILES
CCN1C2=NC(=NC(=C2C=C(C1=O)C3=CC=NN3)C)N
InChi
InChI=1S/C13H14N6O/c1-3-19-11-8(7(2)16-13(14)17-11)6-9(12(19)20)10-4-5-15-18-10/h4-6H,3H2,1-2H3,(H,15,18)(H2,14,16,17)
InChi Key
RGHYDLZMTYDBDT-UHFFFAOYSA-N
Handling
Protect from air and light

Product Categories/Family for XL765 biochemical

Enzyme Inhibitors; Protein Kinase Inhibitors; PI3K/mTOR Inhibitors Biochemicals; Enzyme Inhibitors; Protein Kinase Inhibitors; PI3K/mTOR Inhibitors Signaling Pathways; PI3 K/Akt/mTOR Signaling; Inhibitors; PI 3-K/mTOR Inhibitors Biochemicals; Biochemicals

Structure of XL765 biochemical

XL765 Biochemical – Cat# MBS842087

Other Notes

Small volumes of XL765 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for XL765 purchase

MBS842087 is a biochemical targeting XL765.
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