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MRL-24

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS842108

Background: Cell-permeable. MRL-24 displays high affinity for PPARgamma with excellent anti-diabetic activity in mice but poor PPARgamma agonist activity in transcription and adipogenesis assays. Highly effective (30 nM) at blocking Cdk5-mediated… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
MRL-24, Biochemical
Full Product Name
MRL-24
Product Gene Name
MRL-24 biochemical
Product Synonym Names
(S)-2-(3-((1-(4-methoxybenzoyl)-2-methyl-5-(trifluoromethoxy)-1H-indol-3-yl)methyl)phenoxy)propanoic acid
Form/Format
Appearance: White solid
Purity/Purification
>=98% by TLC
Preparation and Storage
At -20 degree C
Shelf Life: 36 months
Molecular Weight
527.49
Structure Available?
Y
Salt Form
No
Cell-Permeable?
Y
Solubility/Reconstitution Instructions
DMSO (~ 30 mg/ml)
SMILES
CC1=C(CC2=CC(O[C@H](C(O)=O)C)=CC=C2)C3=CC(OC(F)(F)F)=CC=C3N1C(C4=CC=C(OC)C=C4)=O
InChi
InChI=1S/C28H24F3NO6/c1-16-23(14-18-5-4-6-21(13-18)37-17(2)27(34)35)24-15-22(38-28(29,30)31)11-12-25(24)32(16)26(33)19-7-9-20(36-3)10-8-19/h4-13,15,17H,14H2,1-3H3,(H,34,35)
InChi Key
OFCWBJAYEIROGZ-UHFFFAOYSA-N
Handling
Protect from air and light

Product Categories/Family for MRL-24 biochemical

Biochemicals; Activators/Inducers; Agonists; etc.; PPAR AgonistsDiabetes; Obesity & Metabolic Syndrome; Signaling Pathways in Diabetes and Obesity; PPAR Signaling; PPAR AgonistsDiabetes; Obesity & Metabolic Syndrome; Anti-diabetic compounds and Obesity Pe

Structure of MRL-24 biochemical

MRL-24 Biochemical – Cat# MBS842108

Other Notes

Small volumes of MRL-24 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MRL-24 purchase

MBS842108 is a biochemical targeting MRL-24.
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